Clinical Trials in Ohio

Showing 3541-3560 of 20,938 trials

Inspiratory Muscle Training Immediately After Lung Transplantation

NCT05309551

Following lung transplantation (LTX), patients may exhibit respiratory and skeletal muscle weakness that will affect exercise capacity, increase dyspnea and fatigue, limit activities of daily living (ADL) and decrease quality of life. Inspiratory muscle training (IMT) has been extensively studied in a variety of non-LTX populations and research has shown that IMT improves exercise capacity, diaphragmatic thickness, and reduced dyspnea during activities of daily living and improved quality of life in patients with advanced lung disease. The aim of this randomized controlled study is to investigate the benefits of providing inspiratory muscle training via use of an inspiratory muscle trainer device in addition to standard physical therapy in the acute phase of rehabilitation following LTX. Patients targeted for enrollment will be those with any type of advanced lung disease requiring LTX with the objective of demonstrating improvements in respiratory muscle recovery, perceived dyspnea, severity of fatigue, and overall functional status following the transplant procedure.

Lung TransplantationChronic Lung DiseaseMuscle Weakness+1 more

Ohio State University90 participantsStarted Apr 2022

Columbus, Ohio, United States

Active Not RecruitingPhase 432 miles

STEP TEENS Weight Maintenance: A Research Study on How Well Semaglutide Helps Teenagers With Excess Body Weight to Lose Weight and Maintain Weight Loss

NCT06571383

The study is testing how well semaglutide can help adolescents with excess body weight to lose weight and to maintain weight loss. All participants in the study will receive semaglutide as a weekly injection. The study medicine is injected with a thin needle in the stomach, thighs or upper arms. All participants will get semaglutide treatment for a minimum of 3 years.

Obesity

Novo Nordisk A/S500 participantsStarted Sep 2024

Escondido, California, United States • Orlando, Florida, United States • Tallahassee, Florida, United States +90 more locations

Inspiratory Muscle Training Immediately After Lung Transplantation

STEP TEENS Weight Maintenance: A Research Study on How Well Semaglutide Helps Teenagers With Excess Body Weight to Lose Weight and Maintain Weight Loss

Find Trials by Condition in Ohio

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Brain Health in Youth With Normal Weight, Overweight and Obesity at Risk for Type 2 Diabetes (T2D)

Study to Evaluate CCS1477 (Inobrodib) in Haematological Malignancies

A Study of Efficacy, Safety, and Tolerability of KAN-101 in People With Celiac Disease

CBT-I vs. MBTI for Traumatic Brain Injury (TBI)-Related Insomnia and Post-Traumatic Stress Symptoms

The Johns Hopkins Heartburn Center Registry

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Study of Aspirin in Patients With Vestibular Schwannoma

A Phase 3 Study of F14 for Management of Pain Following Total Knee Replacement

Long-Term Follow-Up (LTFU) for Gene Therapy of Leukocyte Adhesion Deficiency-I (LAD-I)

An Observational LTFU Study for Patients Previously Treated With Autologous ex Vivo Gene Therapy for ADA-SCID