Clinical Trials in Ohio

Showing 1981-2000 of 17,983 trials

Rucaparib and Pembrolizumab for Maintenance Therapy in Stage IV Non-Squamous Non-Small Cell Lung Cancer

NCT03559049

This study is a multi-center, Phase I/II, single arm trial to assess the safety and efficacy of the combination of oral rucaparib plus intravenous pembrolizumab as maintenance therapy in patients with stage IV non-squamous non-small cell lung cancer (NSCLC) without progressive disease (PD), as confirmed on CT scans, after induction therapy with carboplatin/pemetrexed/pembrolizumab (CPP) triplet therapy.

Stage IV Non-small Cell Lung Cancer

University of Michigan Rogel Cancer Center25 participantsStarted Dec 2018

Ann Arbor, Michigan, United States • St Louis, Missouri, United States • Columbus, Ohio, United States

RECRUITINGPhase 332 miles

A Randomized Trial to Evaluate Sequential vs Simultaneous Patching

NCT04378790

A randomized trial to determine whether simultaneous treatment with spectacles and patching has an equivalent VA outcome compared with sequential treatment, first with spectacles alone followed by patching (if needed), for previously untreated amblyopia in children 3 to \<13 years of age.

Amblyopia

Jaeb Center for Health Research544 participantsStarted Dec 2020

Birmingham, Alabama, United States • Birmingham, Alabama, United States • Glendale, Arizona, United States +65 more locations

Rucaparib and Pembrolizumab for Maintenance Therapy in Stage IV Non-Squamous Non-Small Cell Lung Cancer

A Randomized Trial to Evaluate Sequential vs Simultaneous Patching

Find Trials by Condition in Ohio

Intratumoral PH-762 for Cutaneous Carcinoma

A First-in-human Study of S230815 in Pediatric Participants With KCNT1-related Developmental and Epileptic Encephalopathy

Dichoptic Treatment for Amblyopia in Children 4 to 7 Years of Age

A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Metastatic Non-squamous NSCLC

Development of a Database to Investigate Digital and Blood-Based Biomarkers and Their Relationship to Tau and Amyloid PET Imaging in Older Participants Who Are Cognitively Normal (CN), Have Mild Cognitive Impairment (MCI), or Have Mild-to-Moderate AD Dementia

A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)

Efficacy and Safety of Clesrovimab (MK-1654) in Infants (MK-1654-004)

A Study to Learn About BNT162b2 (LP.8.1)-Adapted Vaccine Against SARS-CoV-2 in Children 5 Through 11 Years of Age That Are Considered at Higher Risk of Severe COVID-19

A Study of Navenibart in Participants With Hereditary Angioedema

Study of Single Agent Belantamab Mafodotin Versus Pomalidomide Plus Low-dose Dexamethasone (Pom/Dex) in Participants With Relapsed/Refractory Multiple Myeloma (RRMM)

A Proof-of-Concept Study to Assess the Efficacy, Safety and Tolerability of Itepekimab (Anti-IL-33 mAb) in Participants With Non-cystic Fibrosis Bronchiectasis

A Study of AZD0120 in Autoimmune Diseases

An Open-label Study (OLE) for Non-responders of VRDN-001-101 and VRDN-001-301

A Study of Calderasib (MK-1084) in KRAS Mutant Advanced Solid Tumors (MK-1084-001)

Increasing Patients' Engagement in Breast Cancer Surgery Decision-Making

Evaluation of ELU42 Topical Spray for the Treatment of Diabetic Foot Ulcers

Efficacy and Safety of VB119 in Subjects With Membranous Nephropathy

Assessing Feasibility of Prolonged Repetitive Near Infrared Light Stimulation in Early to Mid-Stage Dementia