Clinical Trials in North Carolina

Showing 14881-14900 of 20,428 trials

First Time in Human Study of GSK1223249 in Amyotrophic Lateral Sclerosis

NCT00875446

The drug being tested in this study is GSK1223249. It is being developed by GlaxoSmithKline to treat symptoms in patients with Amyotrophic Lateral Sclerosis (ALS). The drug works by inhibiting the protein that prevents nerve growth. This will be the first time the drug will be given to man. The trial is expected to involve approximately 76 patients. The study objective is to investigate the tolerability, safety and the way the body handles GSK1223249 after a range of single doses or repeat dose escalation in patients with ALS.

Amyotrophic Lateral Sclerosis

GlaxoSmithKline76 participantsStarted May 2009

Baltimore, Maryland, United States • New York, New York, United States • Syracuse, New York, United States +9 more locations

COMPLETEDPhase 246 miles

School Support as Structural HIV Prevention for Adolescent Orphans in Kenya

NCT01501864

The purpose of this study is to test whether school support can keep adolescent Kenyan orphans in school, reduce sexual risk behaviors, and prevent HIV /HSV-2 infection.

HIV

Pacific Institute for Research and Evaluation835 participantsStarted Jul 2011

Chapel Hill, North Carolina, United States • Eldoret, Kenya

First Time in Human Study of GSK1223249 in Amyotrophic Lateral Sclerosis

School Support as Structural HIV Prevention for Adolescent Orphans in Kenya

Find Trials by Condition in North Carolina

A Representational Intervention to Promote Preparation for End-of-life Decision Making

Randomized, Double-Blind, Placebo-Controlled Study of Larazotide Acetate in Subjects With Active Celiac Disease

Physiologic Definition of Bronchopulmonary Dysplasia

Inhaled Nitric Oxide for Preterm Infants With Severe Respiratory Failure

A Phase II, Randomized, Double-blind, Placebo-controlled Study to Examine the Effects of DAS181 in Immunocompromised Subjects With Lower Respiratory Tract Parainfluenza Infection on Supplemental Oxygen

Study to Assess the Efficacy of Larazotide Acetate for the Treatment of Celiac Disease

Oral Rivaroxaban in Children With Venous Thrombosis

Inhaled Nitric Oxide Study for Respiratory Failure in Newborns

The Effects of Erythropoietin (EPO) on the Transfusion Requirements of Very Low Birth Weight Infants

FOTO: Five Consecutive Days on Treatment With Efavirenz, Tenofovir, and Emtricitabine Followed by Two Days Off Treatment Versus Continuous Treatment

Clinical Trials to Reduce the Risk of Antimicrobial Resistance

High Dose Oral 4-Aminosalicylic Acid (PASER®) to Control Acute Flares of Mild to Moderate Crohn's Disease in Children

Clinical Performance of the Accelerate ID/AST System for Positive Blood Culture

Pazopanib Hydrochloride in Treating Patients With Advanced or Progressive Malignant Pheochromocytoma or Paraganglioma

Delayed Cord Clamping in VLBW Infants

Delafloxacin Versus Vancomycin and Aztreonam for the Treatment of Acute Bacterial Skin and Skin Structure Infections

Ispinesib In Combination With Carboplatin In Patients With Solid Tumors

Efficacy, Safety and Tolerability of Multiple Doses of Valsartan in Children With Hypertension With or Without CKD