Clinical Trials in North Carolina

Showing 6081-6100 of 20,428 trials

A Phase 1b Study of Imvotamab in Moderate to Severe Rheumatoid Arthritis

NCT06087406

The purpose of this study is to determine the safety and tolerability of imvotamab in patients with moderate to severe rheumatoid arthritis who have failed prior therapies. Participants will be given imvotamab or placebo through a vein (i.e., intravenously). A placebo is a look-alike substance that contains no active drug

Rheumatoid ArthritisArthritis, RheumatoidArthritis

IGM Biosciences, Inc.33 participantsStarted Mar 2023

Flagstaff, Arizona, United States • Glendale, Arizona, United States • San Diego, California, United States +15 more locations

COMPLETEDPhase 346 miles

An Extension Study to Evaluate Maintenance of Efficacy and Long-term Treatment Effect of Oral Budesonide Suspension (OBS) in Adults and Adolescents With Eosinophilic Esophagitis (EoE)

NCT02736409

This is a multicenter, double- blind extension study of Oral Budesonide Suspension (OBS) in adults and adolescents (11 to 55 years of age, inclusive) with Eosinophilic Esophagitis (EoE) who have completed participation in the SHP621-301 induction study (NCT02605837). The primary objective is to evaluate the maintenance of efficacy of OBS over 36 weeks. Maintenance of efficacy will be measured by the peak eosinophilic count and Dysphagia Symptom Questionnaire (DSQ) score.

Eosinophilic Esophagitis (EoE)

Shire219 participantsStarted Apr 2016

Birmingham, Alabama, United States • Phoenix, Arizona, United States • Tucson, Arizona, United States +59 more locations

A Phase 1b Study of Imvotamab in Moderate to Severe Rheumatoid Arthritis

An Extension Study to Evaluate Maintenance of Efficacy and Long-term Treatment Effect of Oral Budesonide Suspension (OBS) in Adults and Adolescents With Eosinophilic Esophagitis (EoE)

Find Trials by Condition in North Carolina

Wet-to-dry vs Petrolatum & Non-stick Dressings After Hidradenitis Suppurativa Surgery

Neuroblastoma Precision Trial

Tamoxifen in Women With Breast Cancer and in Women at High-Risk of Breast Cancer Who Are Receiving Venlafaxine, Citalopram, Escitalopram, Gabapentin, or Sertraline

A Study Evaluating Safety and Tolerability, and Pharmacokinetics of Navitoclax Monotherapy and in Combination With Ruxolitinib in Participants With Myeloproliferative Neoplasm

A Study to Assess the Safety, Tolerability and Efficacy of IONIS-AGT-LRx in Hypertensive Participants With Uncontrolled Blood Pressure

BioProtect Balloon Implant™ Balloon System Pivotal Study BP-007

INFINITY™Total Ankle Replacement Follow-up

Study of Daily Application of Nestorone® (NES) and Testosterone (T) Combination Gel for Male Contraception

Interventional Study of INCB 99280 With Ipilimumab in Participants With Select Solid Tumors

A Study of KB-0742 in Participants With Relapsed or Refractory Solid Tumors Including Platinum Resistant High Grade Serous Ovarian Cancer (HGSOC)

Mapping the Phenotype in Adults With Phelan-McDermid Syndrome

Safety and Effectiveness of the MiniMed™ 780G System With DS5 CGM

IO-202 as Monotherapy and IO-202 Plus Azacitidine ± Venetoclax in Patients in AML and CMML

P-PSMA-101 CAR-T Cells in the Treatment of Subjects With Metastatic Castration-Resistant Prostate Cancer (mCRPC) and Advanced Salivary Gland Cancers (SGC)

Evaluation of the Safety and Effectiveness of Bilateral Exablate Ablation of the Pallidothalamic Tract (PTT) for the Treatment of the Motor Complications of Parkinson's Disease (PD)

A Study to Assess the Pharmacodynamics of VK0214 in Male Subjects With AMN

A Study to Learn How Well the Study Treatment Zabedosertib (BAY1834845) Works and How Safe it is Compared to Placebo in Adult Participants With Moderate-to-severe Atopic Dermatitis

Study of the Efficacy of Lurasidone in Cognitive Functioning in Bipolar Patients