Clinical Trials in North Carolina

Showing 4061-4080 of 20,428 trials

Solriamfetol in Improving Sleep in Patients With Grade II-IV Glioma

NCT03868943

This phase II trial studies the side effects of solriamfetol in improving sleep in patients with grade II-IV glioma. Solriamfetol is a wakefulness-promoting drug. Giving solriamfetol may improve sleep, memory, fatigue, mood, or quality of life in patients with brain tumors (gliomas).

GliomaGlioblastoma

Wake Forest University Health Sciences2 participantsStarted Jan 2021

Winston-Salem, North Carolina, United States

COMPLETEDPhase 1/241 miles

A Single-ascending Dose (Part A) and Repeat-dose (Part B) Study to Investigate the Safety, Pharmacokinetics and Efficacy (Part B Only) of UCB1381 in Healthy Study Participants (Part A) and in Study Participants With Moderate to Severe Atopic Dermatitis (Part B)

NCT05277571

The purpose of the study is to investigate the safety and tolerability of single-ascending doses of UCB1381 (intravenous and subcutaneous) in healthy study participants and after repeat intravenous dosing in study participants with atopic dermatitis. Efficacy will be assessed following repeat intravenous dosing versus placebo in study participants with atopic dermatitis.

Atopic Dermatitis

UCB Biopharma SRL273 participantsStarted Mar 2022

Beverly Hills, California, United States • Glendale, California, United States • Los Angeles, California, United States +13 more locations

Solriamfetol in Improving Sleep in Patients With Grade II-IV Glioma

A Single-ascending Dose (Part A) and Repeat-dose (Part B) Study to Investigate the Safety, Pharmacokinetics and Efficacy (Part B Only) of UCB1381 in Healthy Study Participants (Part A) and in Study Participants With Moderate to Severe Atopic Dermatitis (Part B)

Find Trials by Condition in North Carolina

A Study of Orforglipron (LY3502970) Compared With Dapagliflozin in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Metformin

Nonhealing Diabetic Foot Ulcers Treated With Standard of Care (SOC) Alone or Standard of Care and Amnion-Intermediate-Chorion (AIC)

Hearing Impairment, Strategies and Outcomes in VA Emergency Departments

GRAVITAS-309: Itacitinib and Corticosteroids as Initial Treatment for Chronic Graft-Versus-Host Disease

Personalized Therapy Study - HFRS (TriageHF) Post Approval Study

An Open Label Study Evaluating the Efficacy and Safety of Etrumadenant (AB928) Based Treatment Combinations in Participants With Metastatic Colorectal Cancer.

A Study of Sovilnesib in Subjects With Ovarian Cancer

Comparing the Extent to Which Three Different Formulations of LY4100511 (DC-853) Are Made Available in the Body, Alone and in the Presence of a Drug That Reduces Stomach Acid

First-in-human Study of DS-1062a for Advanced Solid Tumors (TROPION-PanTumor01)

Gilteritinib for the Treatment of ALK NSCLC

Parametric Response Mapping (PRM) for the Detection of Chronic Lung Injury in Hematopoietic Cell Transplant Recipients

Study of VIR-2218, VIR-3434, and/or PEG-IFNα in Subjects With Chronic Hepatitis B Virus Infection

Study of Daxdilimab (HZN-7734) in Participants With Moderate-to-Severe Primary Discoid Lupus Erythematosus

Azacitidine Combined With Pembrolizumab and Epacadostat in Subjects With Advanced Solid Tumors (ECHO-206)

Improving Postamputation Functioning by Decreasing Phantom Pain With Perioperative Continuous Peripheral Nerve Blocks: A Department of Defense Funded Multicenter Study

A Study in Patients With Atopic Eczema to Test How Effective BI 655130 is and How Well it is Tolerated

A Study of Zolbetuximab (IMAB362) in Adults With Gastric Cancer

Staphylococcus Aureus Network Adaptive Platform Trial