Clinical Trials in New York

Showing 7301-7320 of 22,668 trials

PAK4 and NAMPT in Patients With Solid Malignancies or NHL (PANAMA)

NCT02702492

This study will evaluate the safety, tolerability, and efficacy of oral KPT-9274 for the treatment of patients with advanced solid malignancies or non-Hodgkin's lymphoma (NHL).

Solid TumorsNHL

Karyopharm Therapeutics Inc60 participantsStarted Jun 2016

Los Angeles, California, United States • Aurora, Colorado, United States • Washington D.C., District of Columbia, United States +5 more locations

TERMINATEDPhase 3< 1 mile

Phase 3 Study to Evaluate the Efficacy and Safety of Intravenous BIIB093 (Glibenclamide) for Severe Cerebral Edema Following Large Hemispheric Infarction

NCT02864953

The primary objective of Part 1 of the study is to determine if BIIB093 improves functional outcome at Day 90 as measured by the modified Rankin Scale (mRS) when compared with placebo in participants with Large Hemispheric Infarction (LHI). The secondary objectives of Part 1 of the study are to determine if BIIB093 improves overall survival at Day 90 when compared with placebo, if BIIB093 improves functional outcome at Day 90 on the mRS dichotomized 0-4 vs. 5-6 when compared with placebo, if BIIB093 reduces midline shift at 72 hours (or at time of decompressive craniectomy \[DC\] or comfort measures only \[CMO\], if earlier) when compared with placebo, and to evaluate the safety and tolerability of BIIB093 in participants with LHI. The objectives of Part 2 of the study are to evaluate long-term disability following LHI, to evaluate long-term outcome measures of clinical function, quality of life, and healthcare utilization, and to assess the safety of BIIB093 in subjects with LHI during the follow-up period.

Brain EdemaStroke, Acute

Remedy Pharmaceuticals, Inc.535 participantsStarted Aug 2018

Phoenix, Arizona, United States • Tucson, Arizona, United States • Palo Alto, California, United States +247 more locations

PAK4 and NAMPT in Patients With Solid Malignancies or NHL (PANAMA)

Phase 3 Study to Evaluate the Efficacy and Safety of Intravenous BIIB093 (Glibenclamide) for Severe Cerebral Edema Following Large Hemispheric Infarction

Find Trials by Condition in New York

A Phase 1/2 Trial of SP-101 for the Treatment of Cystic Fibrosis (CF)

Treatment Patterns Among Patients With Venous Thromboembolism in the United States

A Multi Center Study of Sexual Toxicities After Radiotherapy

Pegtibatinase As an Enzyme Therapy for Patients with Homocystinuria Caused by Cystathionine Beta-Synthase Deficiency (COMPOSE)

Analysis of Both Sex and Device Specific Factors on Outcomes in Patients with Non-Ischemic Cardiomyopathy

Study of Pemetrexed + Platinum Chemotherapy With or Without Pembrolizumab (MK-3475) in Adults With Tyrosine Kinase Inhibitor- (TKI)-Resistant Epidermal Growth Factor Receptor- (EGFR)-Mutated Metastatic Non-squamous Non-small Cell Lung Cancer (NSCLC) (MK-3475-789/KEYNOTE-789)

Navitoclax and Sorafenib Tosylate in Treating Patients With Relapsed or Refractory Solid Tumors

Pilot Study to Evaluate the CereVasc® EShunt® System in the Treatment of Communicating Hydrocephalus

Study to Evaluate the Efficacy, Safety, and Tolerability of Mirabegron in Older Adult Subjects With Overactive Bladder (OAB)

First in Human Study of M1069 in Advanced Solid Tumors

Safety and Immunogenicity of RNA-based Vaccines Against SARS-CoV-2 Variants in Healthy Participants

Real-World Evidence (RWE) Data Analysis of 1-year Consecutive Use of Remote Electrical Neuromodulation (REN)

Observational Study to Assess Migraine Prediction Tool

Oxygen Therapy Use in Patients With Fibrotic Interstitial Lung Disease

FPA150 in Patients With Advanced Solid Tumors

Registry of Subjects With Drug Resistant Epilepsy and Treated With the VNS Therapy System.

Glyburide Advantage in Malignant Edema and Stroke Pilot

Adjunctive Fosfomycin for Treatment of Staphylococcus Aureus Bacteraemia