Clinical Trials in New York

Showing 5321-5340 of 22,668 trials

Evaluation of Talazoparib, a PARP Inhibitor, in Patients With Somatic BRCA Mutant Metastatic Breast Cancer: Genotyping Based Clinical Trial

NCT03990896

This research is to evaluate the effectiveness of Talazoparib as a potential treatment for metastatic breast cancer with a BRCA 1 or BRCA 2 mutation.

Breast Cancer

Massachusetts General Hospital30 participantsStarted Nov 2021

San Francisco, California, United States • Atlanta, Georgia, United States • Chicago, Illinois, United States +4 more locations

COMPLETEDPhase 2< 1 mile

Hepcidin Mimetic in Patients With Polycythemia Vera (REVIVE)

NCT04057040

This is a Phase 2 study with an open-label dose escalation phase followed by a blinded withdrawal phase and an open label extension. The study is designed to monitor the PTG-300 safety profile and to obtain preliminary evidence of efficacy of PTG-300 for the treatment of phlebotomy-requiring polycythemia vera.

Polycythemia Vera

Protagonist Therapeutics, Inc.70 participantsStarted Oct 2019

Phoenix, Arizona, United States • Greenbrae, California, United States • Palo Alto, California, United States +13 more locations

Evaluation of Talazoparib, a PARP Inhibitor, in Patients With Somatic BRCA Mutant Metastatic Breast Cancer: Genotyping Based Clinical Trial

Hepcidin Mimetic in Patients With Polycythemia Vera (REVIVE)

Find Trials by Condition in New York

Hemodynamic-GUIDEd Management of Heart Failure

Non-fucosylated Anti-CTLA-4 (BMS-986218) + Degarelix Acetate vs. Degarelix Acetate Alone in Men With High-risk Localized Prostate Cancer

Phase 1, First-in-human, Dose-finding and Expansion Study to Evaluate XmAb®808 in Combination With Pembrolizumab in Advanced Solid Tumors

Dose-Finding Study of Intranasal Midazolam for Procedural Sedation in Children

A Phase 2 Safety and Efficacy Study of Tulisokibart (MK-7240/PRA023) in Subjects With Moderately to Severely Active Ulcerative Colitis (MK-7240-005)

Long Term Extension Study of Tapinarof for Plaque Psoriasis in Adults (3003)

Dipraglurant (ADX48621) for the Treatment of Patients With Parkinson's Disease Receiving Levodopa-based Therapy

OurChild: A Health IT Solution to Reduce Minority Health Disparities

A Study of GC012F (AZD0120), a CAR T Therapy Targeting CD19 and BCMA in Subjects With Relapsed/Refractory Multiple Myeloma

Screening for AL Amyloidosis in Smoldering Multiple Myeloma

The Symptomatic Cerebral Cavernous Malformation Trial of REC-994

A Phase 3B Study to Evaluate Bone Mineral Density With Long-Term Use of Relugolix Combination Tablet in Women With Uterine Fibroids or Endometriosis

Safety and Efficacy of GSK Neisseria Gonorrhoeae GMMA (NgG) Investigational Vaccine When Administered to Healthy Adults 18 to 50 Years of Age.

Phase 3 Study of S-217622 in Prevention of Symptomatic SARS-CoV-2 Infection

Skeletal Health and Bone Marrow Composition Among Youth

Prolonged Overnight Fasting and/or Exercise on Fatigue and Other Patient Reported Outcomes in Women With Hormone Receptor Positive Advanced Breast Cancer

An Extension Study of HGT-HIT-045 Evaluating Long-Term Safety and Clinical Outcomes of Idursulfase-IT in Conjunction With Elaprase in Pediatric Participants With Hunter Syndrome and Cognitive Impairment

A Study to Evaluate the Safety, Tolerability, and Effects on Blood and Urine Markers of Single Ascending Dose of GSK4771261 in Healthy Participants and Participants With Autosomal Dominant Polycystic Kidney Disease