Clinical Trials in New York

Showing 5181-5200 of 22,668 trials

Characterization of the Cardiac Phenotype of Friedreich's Ataxia (FRDA)

NCT02316314

Friedreich's ataxia (FRDA) is an autosomal recessive disease characterized by loss of coordination and cardiomyopathy. It is the most common form of inherited ataxia with an incidence in 1/50,000 in the Caucasian population. FRDA is associated with progressive damage to the nervous system, resulting in symptoms ranging from gait disturbance to speech problems, as well as diabetes and heart disease. The heart disease manifests as cardiomyopathy, and is responsible for approximately 60% of deaths from FRDA. This study is designed to characterize the cardiac manifestations of the disease using exercise, MRI, ECHO and serum parameters, in the context of the neurological disease. In addition, this study will demonstrate that corneal confocal microscopy (CCM) may also provide a biomarker for FRDA.

Friedreich's Ataxia

Weill Medical College of Cornell University100 participantsStarted Jan 2015

New York, New York, United States

Active Not RecruitingNA< 1 mile

Intraoperative Radiation Therapy (IORT) in DCIS

NCT03216421

The goal of this study is to examine the role of Intraoperative Radiotherapy (IORT) in Ductal Carcinoma In-Situ (DCIS) and to improve the understanding of the clinical, radiographic, and patient-related impact of adopting IORT.

Breast CancerDuctal Carcinoma in Situ

Columbia University265 participantsStarted Sep 2017

New York, New York, United States

Characterization of the Cardiac Phenotype of Friedreich's Ataxia (FRDA)

Intraoperative Radiation Therapy (IORT) in DCIS

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ARrest RESpiraTory Failure From PNEUMONIA

Trial of Maintenance With Niraparib- Uterine Serous Carcinoma

Reducing Lung CongestIon Symptoms in Advanced Heart Failure

PRIMARY Ancillary Substudy

Combining Ipilimumab, Degarelix, and Radical Prostatectomy in Men With Newly Diagnosed Metastatic Castration Sensitive Prostate Cancer or Ipilimumab and Degarelix in Men With Biochemically Recurrent Castration Sensitive Prostate Cancer After Radical Prostatectomy

Efficacy and Safety of Benralizumab in Moderate to Very Severe Chronic Obstructive Pulmonary Disease (COPD) With a History of Frequent Exacerbations

Bacteriophage Therapy in Patients With Diabetic Foot Osteomyelitis

Prevention of Hospital Acquired Deconditioning in Hospitalized Acute Leukemia Patients

Trans-arterial Embolization for the Treatment of Facet Pain Due to Facet Arthropathy

Evaluation of the Duration of Effect of Bimatoprost SR in Participants With Open-Angle Glaucoma or Ocular Hypertension

Study of Zanzalintinib (XL092) + Pembrolizumab vs Pembrolizumab in Subjects With PD-L1 Positive Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

Breathwork Intervention for Posttraumatic Stress

Atezolizumab + Sacituzumab Govitecan to Prevent Recurrence in TNBC (ASPRIA)

A Phase II, Multicentre, Randomised, Double-blind, Controlled Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Efficacy of COMP360 in Participants With Recurrent Major Depressive Disorder

Measuring Automated Behavioral Observations & Vocal Expressions (ABOVE)

Study to Evaluate the Efficacy and Safety of PF-07055480 / Giroctocogene Fitelparvovec Gene Therapy in Moderately Severe to Severe Hemophilia A Adults

Study to Assess the Efficacy and Safety of NTRA-2112 on Intestinal Malabsorption in Preterm Infants

A Study to Find the Best Dose of BI 1387446 Alone or in Combination With Ezabenlimab (BI 754091) in Patients With Different Types of Advanced or Metastatic Cancer (Solid Tumors)