Clinical Trials in Nashville

Showing 4921-4940 of 20,298 trials

A First-in-human Study of Multiple Doses of BB-1701 in Subjects With Locally Advanced/Metastatic HER2 Expressing Solid Tumors

NCT04257110

This is an open-label, first-in-human (FIH), phase 1 dose-escalation and cohort expansion study of BB-1701 in subjects with locally advanced/metastatic HER2 expressing solid tumors. The study consists of 2 parts: dose-escalation (Part 1) and cohort expansion (Part 2). Part 1 consists of dose escalation cohorts for determining the maximum tolerated dose (MTD) and recommended Phase 2 dose (RP2D). Part 2 consists of expansion cohorts, including but not limited to breast cancer, gastric/gastroesophageal junction cancer, bladder cancer and colon cancer, for exploring 1 or more RP2Ds or schedules for expanding/deepening the information/knowledge about clinical safety, clinical pharmacokinetics and anti-tumor activity.

Locally Advanced/Metastatic HER2 Positive Solid Tumors

Bliss Biopharmaceutical (Hangzhou) Co., Ltd117 participantsStarted Jul 2020

San Francisco, California, United States • Nashville, Tennessee, United States • Fairfax, Virginia, United States +9 more locations

RECRUITINGPhase 2< 1 mile

A Study to Evaluate the Safety and Efficacy of NEXAGON® (Lufepirsen Ophthalmic Gel) in Subjects With PCED

NCT05966493

This study is to evaluate the safety and efficacy of NEXAGON® (lufepirsen ophthalmic gel) (NEXAGON) in subjects with persistent corneal epithelial defects (PCED). The objectives of the study are to evaluate the safety and efficacy of NEXAGON in this population.

Persistent Corneal Epithelial Defect

Glaukos Corporation84 participantsStarted Aug 2023

Dothan, Alabama, United States • Petaluma, California, United States • Torrance, California, United States +25 more locations

A First-in-human Study of Multiple Doses of BB-1701 in Subjects With Locally Advanced/Metastatic HER2 Expressing Solid Tumors

A Study to Evaluate the Safety and Efficacy of NEXAGON® (Lufepirsen Ophthalmic Gel) in Subjects With PCED

Find Trials by Condition in Nashville

Evaluating the Safety and Efficacy of Tradipitant vs. Placebo in Idiopathic and Diabetic Gastroparesis

A Study to Evaluate the Efficacy and Safety of Faricimab in Participants With Neovascular Age-Related Macular Degeneration (TENAYA)

Genetic Testing to Select Therapy for the Treatment of Advanced or Metastatic Kidney Cancer, OPTIC RCC Study

Wavefront-guided LASIK for Monovision Treatment of Myopic Subjects With Presbyopia

This Study Will Collect Clinical and Patient Reported Experience Data From Participants Requiring Urine Output Management Overnight in the Home Setting.

Study of Efficacy, Safety, and Tolerability of LNA043 in Patients With Knee Osteoarthritis

A Study to Assess the Safety and Immune Response of a Vaccine Against Influenza in Healthy Younger and Older Adults

SI-6603 (Condoliase) Study for Lumbar Disc Herniation (Discovery 6603 Study)

A Study of Nivolumab and Ipilimumab in Untreated Participants With Stage 3 Non-small Cell Lung Cancer (NSCLC) That is Unable or Not Planned to be Removed by Surgery

Study Evaluating the Safety and Efficacy of AR-15512 (COMET-3)

A-LiNK: Improving Outcomes in Autoimmune Liver Disease

Virtual Care to Improve Heart Failure Outcomes (VITAL-HF)

A Study of Retatrutide (LY3437943) in Participants With Obesity and Cardiovascular Disease

Pre-IVF Treatment With a GnRH Antagonist in Women With endometriosis_temp

Evaluation of Cataract Surgery Outcomes in Patients With Prior Laser Vision Correction Implanted With the CT LUCIA Lens

A Study of Ibrutinib With Rituximab in People With Untreated Marginal Zone Lymphoma

Evaluation of Alcon Ladarvision Wavefront-Guided PRK

A Phase 2b/3a Study to Evaluate the Efficacy and Safety of JointStem in Patients Diagnosed as Knee Osteoarthritis