Clinical Trials in Minneapolis

Showing 7701-7720 of 14,456 trials

Study of Danicopan in Participants With Normal Kidney Function and Participants With Kidney Dysfunction

NCT04935294

This was an open-label, nonrandomized, multi-center, single-dose, parallel group study to evaluate the effect of severe renal impairment (RI) on the safety, tolerability, pharmacokinetics, and pharmacodynamics of danicopan (ACH-0144471) compared to demographically-matched healthy participants with normal renal function.

HealthyRenal Dysfunction

Alexion Pharmaceuticals, Inc.16 participantsStarted Jan 2018

Miami, Florida, United States • Orlando, Florida, United States • Minneapolis, Minnesota, United States +1 more locations

COMPLETEDPhase 2< 1 mile

Lung-MAP: Talazoparib in Treating Patients With HRRD Positive Recurrent Stage IV Squamous Cell Lung Cancer

NCT03377556

This phase II trial studies how well talazoparib works in treating patients with homologous recombination repair deficiency (HRRD) positive stage IV squamous cell lung cancer that has come back after previous treatment. Talazoparib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

ATM Gene MutationATR Gene MutationBARD1 Gene Mutation+18 more

SWOG Cancer Research Network51 participantsStarted Mar 2017

Birmingham, Alabama, United States • Anchorage, Alaska, United States • Anchorage, Alaska, United States +1154 more locations

Study of Danicopan in Participants With Normal Kidney Function and Participants With Kidney Dysfunction

Lung-MAP: Talazoparib in Treating Patients With HRRD Positive Recurrent Stage IV Squamous Cell Lung Cancer

Find Trials by Condition in Minneapolis

A 6-week Dose Ranging Study of CHF 5259 pMDI in Subjects With Chronic Obstructive Pulmonary Disease

Long-Term Analgesic Efficacy And Safety Of Tanezumab Alone Or In Combination With Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) Versus NSAIDs Alone In Patients With Osteoarthritis Of The Knee Or Hip

Chlorhexidine Gluconate Cleansing in Preventing Central Line Associated Bloodstream Infection and Acquisition of Multi-drug Resistant Organisms in Younger Patients With Cancer or Undergoing Donor Stem Cell Transplant

Long-Term Safety and Tolerability Study of NKTR-181 in Subjects With Chronic Low Back Pain or Chronic Non-Cancer Pain

Efficacy and Safety of Sotagliflozin Versus Placebo in Patients With Type 2 Diabetes Mellitus Not Currently Treated With Antidiabetic Therapy

Safety and Efficacy Study of Sotagliflozin on Glucose Control in Participants With Type 2 Diabetes, Moderate Impairment of Kidney Function, and Inadequate Blood Sugar Control

Efficacy and Safety Trial of Flexible Doses of Oral Ziprasidone in Children and Adolescents With Bipolar I Disorder

An Extension Study of the Safety and Anti-leukemic Effects of Imatinib Mesylate in Participants With Philadelphia Chromosome-positive Chronic Myeloid Leukemia in Blast Crisis

Safety and Efficacy of Bexagliflozin Compared to Sitagliptin as Add-on Therapy to Metformin in Type 2 Diabetes Subjects

Regimen Optimization Study

Observational Study Evaluating Long-term Health Outcomes of Canadian DUODOPA-treated Patients

Safety and Efficacy of Efavaleukin Alfa in Subjects With Active Rheumatoid Arthritis

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Prophylactic Emicizumab Versus no Prophylaxis in Hemophilia A Participants With Inhibitors

Study of INT-747 as Monotherapy in Participants With Primary Biliary Cirrhosis (PBC)

A Pragmatic Randomized Control Trial Comparing Models of Care in the Management of Prescription Opioid Misuse

Improving Outcomes in Cleft Palate Surgery

Efficacy Study of MCS110 Given With Carboplatin and Gemcitabine in Advanced Triple Negative Breast Cancer (TNBC)

Study of DPX-Survivac Therapy in Patients With Recurrent Ovarian Cancer