Clinical Trials in Minneapolis

Showing 6561-6580 of 14,456 trials

Working Toward the Advancement of Recovery Using Modulated Therapeutic Hyperthermia (WARMTH) in Sepsis - Pilot

NCT04961151

The purpose of this pilot study is to demonstrate the ability to warm critically ill patients with sepsis to a target temperature of 39°C

Sepsis

Nicholas M MohrStarted Aug 2021

Iowa City, Iowa, United States • Minneapolis, Minnesota, United States • St Louis, Missouri, United States

TERMINATEDPhase 1/2< 1 mile

GTB-3550 Tri-Specific Killer Engager (TriKE®) for High Risk Hematological Malignancies

NCT03214666

This is a multi-center Phase I/II clinical trial of GTB-3550 (CD16/IL-15/CD33) tri-specific killer cell engager (TriKE®) for the treatment of CD33-expressing high risk myelodysplastic syndromes, refractory/relapsed acute myeloid leukemia or advanced systemic mastocytosis. The hypothesis is that GTB-3550 TriKE® will induce natural killer cell function by targeting malignant cells as well as CD33+ myeloid derived suppressor cells (MDSC) which contribute to tumor induced immunosuppression. Because CD16 is the most potent activating receptor on natural killer (NK) cells, this single agent may induce a targeted anti-CD33+ tumor response.

High-risk Myelodysplastic SyndromesAcute Myelogenous LeukemiaSystemic Mastocytosis+1 more

GT Biopharma, Inc.12 participantsStarted Jan 2020

Minneapolis, Minnesota, United States • Madison, Wisconsin, United States

Working Toward the Advancement of Recovery Using Modulated Therapeutic Hyperthermia (WARMTH) in Sepsis - Pilot

GTB-3550 Tri-Specific Killer Engager (TriKE®) for High Risk Hematological Malignancies

Find Trials by Condition in Minneapolis

e-Cigarette - DNA Adducts

Pembrolizumab With Talimogene Laherparepvec or Placebo in Unresected Melanoma

Clinical Performance of Two Commercial, Daily Disposable Contact Lenses

LDL-C Assessment With PCSK9 Monoclonal Antibody Inhibition Combined With Statin Therapy-2

TruGraf® Long-term Clinical Outcomes Study

Predictive Assay for Decision Making in Adjuvant Therapy

Topical Ruxolitinib Evaluation in Chronic Hand Eczema Study 2

A Study of Escitalopram in the Treatment of Children and Adolescents With Generalized Anxiety Disorder

A Safety Study Comparing LY2140023 to Atypical Antipsychotic Standard Treatment in Schizophrenic Patients

Long-Term Study of Hydrocodone Bitartrate Controlled-release Capsules in Subjects With Chronic Pain

A Study of Polatuzumab Vedotin (DCDS4501A) in Combination With Rituximab or Obinutuzumab Plus Bendamustine in Participants With Relapsed or Refractory Follicular or Diffuse Large B-Cell Lymphoma

Safety, Tolerability, and Efficacy of IONIS-GHR-LRx in Participants With Acromegaly Being Treated With Long-acting Somatostatin Receptor Ligands

Ipilimumab in Treating Patients With Metastatic or Recurrent Human Papilloma Virus-Related Cervical Cancer

Phase 3 Study With Carfilzomib and Dexamethasone Versus Bortezomib and Dexamethasone for Relapsed Multiple Myeloma Patients

Sotrovimab Expanded Access Treatment Protocol (COVID-19)

Ultrasound Markers of Organ Congestion in Severe Acute Kidney Injury

A Study to Investigate CSL312 in Subjects With Hereditary Angioedema (HAE)

Vascular Inflammation in Psoriasis - Apremilast