Clinical Trials in Minneapolis

Showing 5621-5640 of 14,456 trials

Hybrid Closed Loop Therapy and Verapamil for Beta Cell Preservation in New Onset Type 1 Diabetes (CLVer): Extension Study

NCT06177691

The purpose of this extension study is to continue to follow the participants who completed the CLVer RCT for up to 3 additional years. The goal for Cohort A is to evaluate the longer-term effects of verapamil on preservation of β-cell function as measured by C-peptide levels obtained during a mixed meal tolerance test (MMTT). For both Cohorts A and B, the goal is to determine if the high degree of glycemic control achieved during CLVer with HCL can be maintained once the intensive engagement of the study team is discontinued. At the completion of the RCT, study treatments end. Thus, during the extension study, diabetes management is performed as part of usual care and there is no study treatment.

Type1 Diabetes

Jaeb Center for Health Research77 participantsStarted May 2021

Palo Alto, California, United States • Aurora, Colorado, United States • New Haven, Connecticut, United States +3 more locations

COMPLETEDPhase 2< 1 mile

A Study of RVT-1401 in Myasthenia Gravis (MG) Patients

NCT03863080

The purpose of the current study is to assess safety/tolerability and key pharmacodynamic (PD) effects that are considered to be associated with clinical benefit (reduction of total IgG and anti-AChR-IgG) in Myasthenia Gravis patients following treatment with RVT-1401 (also known as IMVT-1401) compared to placebo.

Myasthenia Gravis

Immunovant Sciences GmbH17 participantsStarted May 2019

Mobile, Alabama, United States • Phoenix, Arizona, United States • Carlsbad, California, United States +17 more locations

Hybrid Closed Loop Therapy and Verapamil for Beta Cell Preservation in New Onset Type 1 Diabetes (CLVer): Extension Study

A Study of RVT-1401 in Myasthenia Gravis (MG) Patients

Find Trials by Condition in Minneapolis

A Study of OCE-205 in Participants With Cirrhosis With Ascites Who Developed Hepatorenal Syndrome-Acute Kidney Injury

Study to Test the Efficacy and Safety of Padsevonil as Adjunctive Treatment of Focal-onset Seizures in Adults With Drug-resistant Epilepsy

Reveal LINQ Respiration Clinical Study

Step and Walking Pattern From Cardiac Monitor Study

Derazantinib in Subjects With FGFR2 Gene Fusion-, Mutation- or Amplification- Positive Inoperable or Advanced Intrahepatic Cholangiocarcinoma

Filgotinib in the Induction and Maintenance of Remission in Adults With Moderately to Severely Active Crohn's Disease

Survival Prolongation by Rationale Innovative Genomics

A Study to Assess the Safety, Efficacy and Tolerability of AZD8233 Treatment in Participants With Hyperlipidaemia

Shockwave Medical Peripheral Lithoplasty System Study for PAD (Disrupt PAD III)

Phase II Trial of Combination Immunotherapy With NeuVax and Trastuzumab in High-risk HER2+ Breast Cancer Patients

A Study to Determine the Efficacy and Safety of Luspatercept in Adults With Non Transfusion Dependent Beta (β)-Thalassemia

A Clinical Trial to Confirm Safety & Effectiveness of the SYNERGY 4.50 mm and 5.00 mm Stent for Treatment of Atherosclerotic Lesion(s)

A Clinical Study Evaluating Nivolumab-containing Treatments in Patients With Advanced Non-small Cell Lung Cancer After Failing Previous PD-1/(L)1 Therapy and Chemotherapy

Opioid Use Disorder in the Emergency Department: CTN 0069

Intranasal Oxytocin for Frontotemporal Dementia

The Canadian/US Integrative Oncology Study

iCanCope With Sickle Cell Pain

Study to Evaluate the Safety and Activity (Including Distribution) of 177Lu-3BP-227 in Subjects With Solid Tumours Expressing Neurotensin Receptor Type 1.