Clinical Trials in Minneapolis

Showing 2041-2060 of 12,418 trials

VIRTUUS Children's Study

NCT03719339

The objective of the VIRTUUS Children's Study is to adapt identified and validated adult noninvasive diagnostic and prognostic biomarkers for the characterization of allograft status in pediatric recipients of kidney allografts.

Renal Transplant RejectionPediatric Kidney DiseaseEnd Stage Renal Disease+4 more

Children's Hospital of Philadelphia445 participantsStarted Aug 2017

La Jolla, California, United States • Los Angeles, California, United States • Los Angeles, California, United States +10 more locations

RECRUITING< 1 mile

Surgical Site Infections and the Microbiome: Understanding the Pathogenesis of Surgical Site Infections

NCT06300892

This is a prospective, observational study of patients undergoing open GI surgery. At the time of operation, samples will be collected from the incision site and GI tract. The study will follow patients up to 30 days postoperatively, monitoring for signs of SSI. Samples will be taken from all patients who develop SSI. Sequencing will be performed on a subset of samples based on our specific aims. * Aim 1: conduct a case-control study of patients with SSI and age-, sex-, diagnosis-, and wound class-matched control patients without SSI, comparing microbiome alpha diversity and community composition with 16S RNA sequencing to determine the association with SSI. * Aim 2: identify the strain of bacteria isolated from SSIs using shotgun metagenomic sequencing and determine whether the specific strain was present in the skin and gut at the time of operation.

Open GI Surgery

University of Minnesota300 participantsStarted Apr 2024

Minneapolis, Minnesota, United States

VIRTUUS Children's Study

Surgical Site Infections and the Microbiome: Understanding the Pathogenesis of Surgical Site Infections

Find Trials by Condition in Minneapolis

A Study of Zigakibart in Adults With IgA Nephropathy

Evaluation of A Clinical Diagnostic Test for CRDS

Ganciclovir to Prevent Reactivation of Cytomegalovirus in Patients With Acute Respiratory Failure and Sepsis

A Research Study to Look at How Well CagriSema Helps People Living With Obesity Lose Weight and Maintain Weight Loss in the Long-term

A Trial to Evaluate the Efficacy and Safety of PQ912 in Patients With Early AD

Safely Optimizing Body Weight With TCMCB07 in Patients With Newly Diagnosed Metastatic Colorectal Cancer Undergoing Chemotherapy

Efficacy and Safety of Lorundrostat in Subjects With Uncontrolled and Resistant Hypertension

A Research Study to Compare Two Semaglutide Medicines in People With Type 2 Diabetes

A Study to Evaluate the Efficacy, Safety, and Tolerability of IMVT-1402 in Adult Participants With Active, Difficult to Treat Rheumatoid Arthritis

Study of Cabozantinib in Combination With Atezolizumab Versus Sorafenib in Participants With Advanced Hepatocellular Carcinoma (HCC) Who Have Not Received Previous Systemic Anticancer Therapy

A Study of Olezarsen (Formerly Known as AKCEA-APOCIII-LRX) Administered to Adults With Familial Chylomicronemia Syndrome (FCS) Previously Treated With Volanesorsen

A Study to Assess the Safety, Tolerability, and Efficacy of Rocatinlimab in Adolescent Participants With Moderate-to-severe Atopic Dermatitis (AD)

A Study to Assess the Long-Term Safety and Efficacy of Donidalorsen in the Prophylactic Treatment of Hereditary Angioedema (HAE)

Extension Study to Evaluate Safety and Tolerability of Oral Dersimelagon (MT-7117) in Subjects With Erythropoietic Protoporphyria (EPP) or X-Linked Protoporphyria (XLP)

An Open-label Extension Trial of CVL-865 as Adjunctive Therapy in the Treatment of Focal Onset Seizures

A Study Evaluating The Efficacy and Safety of Neoadjuvant Immunotherapy Combinations in Patients With Surgically Resectable Hepatocellular Carcinoma

A Study of Nofazinlimab (CS1003) in Subjects With Advanced Hepatocellular Carcinoma

Adjunctive Cannabidiol for Recovery From Opioid Study