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Clinical Trials in Miami | 11,431 Studies Near You | Clareo Health

Clinical Trials LocationsMiami

Clinical Trials in Miami

Discover 11,431 clinical trials near Miami, Florida. Find research studies in your area.

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Breast Cancer Lung Cancer Prostate Cancer Colorectal Cancer Melanoma Leukemia Lymphoma Pancreatic Cancer

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Showing 5641-5660 of 11,431 trials

COMPLETEDNA< 1 mile

Percutaneous Endovascular Aneurysm Repair (PEVAR) Trial

NCT01070069

To determine the safety and effectiveness of PEVAR.

Abdominal Aortic Aneurysm

Endologix192 participantsStarted Apr 2010

Loma Linda, California, United States • San Diego, California, United States • Fort Lauderdale, Florida, United States +17 more locations

COMPLETEDPhase 2/3< 1 mile

A Study of Granexin® Gel for the Reduction of Scar Formation in Surgical Wounds Following Bilateral Anchor Incision Breast Surgery

NCT04331080

The purpose of this study is to evaluate effectiveness of Granexin® gel in reducing scar formation in surgical incisional wounds.

MammoplastyScarringScar+1 more

Xequel Bio, Inc.184 participantsStarted Jul 2020

Los Angeles, California, United States • Pasadena, California, United States • Doral, Florida, United States +8 more locations

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Breast Cancerin Miami Lung Cancerin Miami Prostate Cancerin Miami Colorectal Cancerin Miami Melanomain Miami Leukemiain Miami Lymphomain Miami Pancreatic Cancerin Miami Ovarian Cancerin Miami Brain Cancerin Miami Diabetesin Miami

Data from ClinicalTrials.govTerms

COMPLETEDNA< 1 mile

Advancing Child Competencies by Extending Supported Services (ACCESS) for Families Program

NCT03260816

The Advancing Child Competencies by Extending Supported Services (ACCESS) for Families Program is a study funded by the National Institutes of Health to explore behavior and developmental problems among young children aging out of Early Steps (Part C). All families will participate in five evaluations in their home to learn more about their child's behavior and development. Families also may receive treatment designed to help change their child's behaviors that will be conducted over the Internet using a tablet.

Developmental DelayDisruptive Behavior

Florida International University150 participantsStarted Mar 2016

Miami, Florida, United States • Miami, Florida, United States • Palmetto Bay, Florida, United States

COMPLETEDPhase 3< 1 mile

Radiation Therapy With or Without Optional Tamoxifen in Treating Women With Ductal Carcinoma in Situ

NCT00003857

RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Estrogen can stimulate the growth of breast cancer cells. Hormone therapy using tamoxifen may fight breast cancer by blocking the uptake of estrogen by the tumor cells. It is not yet known if radiation therapy is more effective than observation, with or without tamoxifen, in treating ductal carcinoma in situ. PURPOSE: Randomized phase III trial to compare the effectiveness of radiation therapy with that of observation, with or without tamoxifen, in treating women who have ductal carcinoma in situ.

Radiation Therapy Oncology Group636 participantsStarted Dec 1999

Mobile, Alabama, United States • Fairbanks, Alaska, United States • Phoenix, Arizona, United States +366 more locations

COMPLETEDPhase 3< 1 mile

Efficacy and Safety of Vedolizumab Subcutaneously (SC) as Maintenance Therapy in Ulcerative Colitis

NCT02611830

The purpose of this study is to assess the effect of vedolizumab subcutaneous (vedolizumab SC) maintenance treatment on clinical remission at Week 52 in participants with moderately to severely active ulcerative colitis (UC) who achieved clinical response following administration of vedolizumab intravenous (vedolizumab IV) induction therapy.

Colitis, Ulcerative

Takeda383 participantsStarted Dec 2015

Little Rock, Arkansas, United States • Wheat Ridge, Colorado, United States • Middletown, Connecticut, United States +171 more locations

WITHDRAWNNA< 1 mile

Exercise Induced Hypoalgesia Diabetes

NCT05296642

The purpose of this research study is to learn whether different forms of exercise can reduce pain experienced by individuals with painful diabetic peripheral neuropathy.

Diabetic Peripheral NeuropathyDiabetic Peripheral Neuropathic Pain

University of MiamiStarted Aug 2022

Miami, Florida, United States

UNKNOWNPhase 2< 1 mile

Combination Chemotherapy With or Without Hypofractionated Radiation Therapy Before Surgery in Treating Patients With Pancreatic Cancer

NCT02839343

This randomized phase II trial studies how well combination chemotherapy (mFOLFIRINOX) with or without hypofractionated radiation therapy before surgery works in patients with pancreatic cancer that can be removed by surgery. Drugs used in combination chemotherapy, such as oxaliplatin, leucovorin calcium, fluorouracil, and irinotecan hydrochloride, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Hypofractionated radiation therapy delivers higher doses of radiation therapy over a shorter period of time and may kill more tumor cells and have fewer side effects. It is not yet known if combination chemotherapy is more effective with or without hypofractionated radiation therapy before surgery in treating patients with pancreatic cancer.

Pancreatic AdenocarcinomaBorderline Resectable Adenocarcinoma of the Head of the Pancrease

Alliance for Clinical Trials in Oncology126 participantsStarted Dec 2016

Mobile, Alabama, United States • Mobile, Alabama, United States • Mobile, Alabama, United States +152 more locations

COMPLETEDPhase 27.3 miles

Evaluation of Upper GI Ulceration Induced by PL2200 Versus Aspirin in At-Risk Subjects

NCT01646814

This trial is a Phase 2, randomized, controlled study to compare the degree of mucosal injury after the oral administration of an investigational product, PL2200, and a marketed 325 mg immediate-release aspirin product.

Gastroduodenal Ulceration

PLx Pharma247 participantsStarted Sep 2012

Jupiter, Florida, United States • South Miami, Florida, United States • Towson, Maryland, United States +7 more locations

COMPLETEDPhase 28.9 miles

Study of the Safety and Efficacy of Elagolix in Women With Polycystic Ovary Syndrome

NCT03951077

This study will assess the potential impact of elagolix on disordered pituitary and ovarian hormones in women with polycystic ovary syndrome (PCOS).

Polycystic Ovary Syndrome

AbbVie118 participantsStarted Aug 2019

Birmingham, Alabama, United States • Mobile, Alabama, United States • San Diego, California, United States +51 more locations

COMPLETEDPhase 1/214 miles

Open Label, Dose Escalation Study for the Safety and Efficacy of STP705 in Adult Patients With isSCC

NCT04293679

This is an open label, dose escalation study to evaluate the safety and efficacy of intralesional injection of STP705 in adult patients with Cutaneous Squamous Cell Carcinoma in situ (isSCC, Bowen's disease). The purpose of this trial is to evaluate the safety, tolerability and efficacy of various doses of STP705 administered as Intralesional injection in subjects with isSCC. Goals: * To determine the safe and effective recommended dose of STP705 for the treatment of isSCC. * Analysis of biomarkers common to isSCC formation pathway including TGF-β1 and COX-2.

Bowen's DiseaseCutaneous Squamous Cell Carcinoma in Situ

Sirnaomics25 participantsStarted Mar 2019

Aventura, Florida, United States

COMPLETED25 miles

A Study to Assess the Effectiveness of the Nautilus BrainPulse™ as an Aid in the Diagnosis of Concussion

NCT02660164

The objective of the study is to evaluate, in a blinded fashion, the effectiveness of the Nautilus BrainPulse device when used as an aid in the diagnosis of concussion.

Jan Medical, Inc.149 participantsStarted Nov 2015

Fort Lauderdale, Florida, United States • Munster, Indiana, United States • Baton Rouge, Louisiana, United States +1 more locations

COMPLETEDNA27 miles

Endoesophageal Brachytherapy for Patients With Esophageal Cancer

NCT03335813

Depending upon the cancer stage, esophageal cancer can be treated with surgery, chemotherapy, radiation therapy, or a combination of these modalities. Sometimes in addition to external radiation therapy or instead of external radiation therapy, select patients with esophageal cancer may benefit from localized radiation to the tumor, called esophageal brachytherapy. There are many different radiation techniques and delivery approaches for this type of specialized radiation therapy, and the purpose of this document is to provide a written summary of an innovative delivery method.

Esophageal Cancer

Case Comprehensive Cancer Center7 participantsStarted Mar 2018

Weston, Florida, United States

COMPLETEDPhase 242 miles

A Study to Assess the PK and Pharmacodynamics of IPX203 in Subjects With Advanced Parkinson's Disease

NCT03007888

Primary Objective: To compare the pharmacokinetics (PK) of single and multiple doses of IPX203 with Immediate release carbidopa-levodopa (IR CD-LD) in subjects with advanced Parkinson's disease (PD). Secondary Objectives: To compare the pharmacodynamics of single and multiple doses of IPX203 with IR CD-LD. To compare the efficacy of IPX203 with IR CD-LD following multiple doses. To evaluate the safety of IPX203.

Advanced Parkinson's Disease

Impax Laboratories, LLC28 participantsStarted Nov 2016

Little Rock, Arkansas, United States • Little Rock, Arkansas, United States • Boca Raton, Florida, United States +8 more locations

COMPLETEDPhase 1299 miles

Study of SBP-101 Combined With Nab-Paclitaxel and Gemcitabine in Pancreatic Cancer

NCT03412799

This is an open-label phase 1A/1B study to assess the safety, tolerability and pharmacokinetics of SBP-101 when combined with nab-paclitaxel and gemcitabine in subjects with previously untreated metastatic pancreatic ductal adenocarcinoma and to identify a recommended phase 2 dose. The study will also assess preliminary efficacy of the 3-drug treatment combination.

Pancreatic Cancer MetastaticPancreatic Cancer Stage IVStage IV Pancreatic Cancer

Panbela Therapeutics, Inc.50 participantsStarted Jun 2018

La Jolla, California, United States • Gainesville, Florida, United States • Rochester, New York, United States +4 more locations

COMPLETEDPhase 2328 miles

A Study of LJPC-401 for the Treatment of Iron Overload in Adult Patients With Hereditary Hemochromatosis

NCT03395704

This study is a Phase 2 multicenter, randomized, placebo controlled, single-blind study. The primary objective of the study is to compare the effect of weekly dosing of LJPC-401 (synthetic human hepcidin) versus placebo on transferrin saturation (TSAT) in an adult hereditary hemochromatosis patient population.

Hereditary Hemochromatosis

La Jolla Pharmaceutical Company70 participantsStarted Nov 2017

North Little Rock, Arkansas, United States • Los Angeles, California, United States • Palo Alto, California, United States +28 more locations

COMPLETEDPhase 2485 miles

Radiation Therapy in Treating Patients With Prostate Cancer

NCT01434290

RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. Specialized radiation therapy that delivers a high dose of radiation directly to the tumor may kill more tumor cells and cause less damage to normal tissue. Given radiation therapy in different ways may kill more tumor cells. PURPOSE: This randomized phase II trial studies radiation therapy to see how well it works in treating patients with prostate cancer.

Prostate CancerPsychosocial Effects of Cancer and Its TreatmentRadiation Toxicity+1 more

Radiation Therapy Oncology Group255 participantsStarted Sep 2011

Birmingham, Alabama, United States • Peoria, Arizona, United States • Phoenix, Arizona, United States +34 more locations

COMPLETEDPhase 3606 miles

A Study to Evaluate Efficacy and Safety of AG-348 in Not Regularly Transfused Adult Participants With Pyruvate Kinase Deficiency (PKD)

NCT03548220

Study AG348-C-006 evaluated the efficacy and safety of orally administered AG-348 as compared with placebo in participants with pyruvate kinase (PK) deficiency, who were not regularly receiving blood transfusions. Participants were randomized 1:1 to receive either AG-348 or a matching placebo.

Pyruvate Kinase DeficiencyAnemia, Hemolytic

Agios Pharmaceuticals, Inc.80 participantsStarted Aug 2018

Little Rock, Arkansas, United States • Atlanta, Georgia, United States • Indianapolis, Indiana, United States +43 more locations

TERMINATEDPhase 3705 miles

Combination Entecavir and Peginterferon Therapy in HBeAg-Positive Immune-Tolerant Adults With Chronic Hepatitis B

NCT01369199

The investigators evaluated the safety and efficacy of a short lead-in course (8 weeks) of entecavir followed by combination of entecavir plus peginterferon alfa-2a for 40 weeks.

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)28 participantsStarted May 2012

Los Angeles, California, United States • Los Angeles, California, United States • San Francisco, California, United States +18 more locations

COMPLETEDPhase 21191 miles

Study to Determine the Dose, the Safety and Effectiveness of a New Drug, Modified Release rhTSH, in Patients With Multinodular Goiter

NCT00454220

The purpose of this study is to determine the safety and effectiveness of 2 different doses of modified-release recombinant human thyroid stimulating hormone (MRrhTSH) when administered with radioiodine in patients with multinodular goiter, a condition that involves the enlargement of the thyroid gland. We will also evaluate the safety and effectiveness of radioiodine therapy alone in these patients. The goal of the treatment is to determine if there was a reduction in the size of the goiter and to study if goiter symptoms have improved after 6 months and after 36 months.

Multinodular Goiter

Genzyme, a Sanofi Company96 participantsStarted Jul 2007

Boston, Massachusetts, United States • Curitiba, Brazil • Rio de Janeiro, Brazil +8 more locations

COMPLETEDPhase 21283 miles

Ahmed Glaucoma Valve Surgery With Mitomycin-C

NCT02805257

This study will determine the effectiveness of Mitomycin-C use in the glaucoma surgery Ahmed valve implantation. Approximately 100 patients will be enrolled, with half receiving the Mitomycin-C treatment and the other half receiving placebo treatment.

GlaucomaPrimary Open Angle GlaucomaSecondary Glaucoma+1 more

University of California, San Francisco119 participantsStarted Jun 2016

San Francisco, California, United States • Guangzhou, Guangdong, China • Raipur, Chhattisgarh, India +1 more locations

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