Clinical Trials in Massachusetts

Showing 3201-3220 of 15,316 trials

The IDEA Study (Individualized Decisions for Endocrine Therapy Alone)

NCT02400190

This study will collect rates of local/regional recurrence in select patients who do not receive radiation treatment after lumpectomy surgery. These women must be postmenopausal; have hormone receptor-positive, Her2-negative tumors; have Oncotype-DX RS less than or equal to 18; and plan to receive endocrine therapy. In this way, this study seeks to collect prospective data supporting the idea that this is a population at sufficiently low risk of local/regional recurrence that omission of adjuvant radiation might be a reasonable option.

Breast Neoplasms

University of Michigan Rogel Cancer Center202 participantsStarted May 2015

Stanford, California, United States • New Haven, Connecticut, United States • Maywood, Illinois, United States +10 more locations

RECRUITINGPhase 326 miles

The Cancer of the Pancreas Screening-5 CAPS5)Study

NCT02000089

Johns Hopkins clinical research office quality assurance group will monitor and audit this study at Johns Hopkins. The Sub Investigator at each site will be responsible for internal monitoring at their site.

Pancreas CancerPeutz-Jeghers Syndrome (PJS)Gene Mutation+2 more

Johns Hopkins University9,000 participantsStarted Jan 2014

New Haven, Connecticut, United States • Baltimore, Maryland, United States • Boston, Massachusetts, United States +6 more locations

The IDEA Study (Individualized Decisions for Endocrine Therapy Alone)

The Cancer of the Pancreas Screening-5 CAPS5)Study

Find Trials by Condition in Massachusetts

A Study to Assess the Safety, Tolerability, and Effect on Disease Progression of BIIB105 in Participants With Amyotrophic Lateral Sclerosis (ALS) and Participants With the ALS Ataxin-2 (ATXN2) Genetic Mutation

The COMPASSION Study

Chemotherapy and Radiation Therapy With or Without Metformin Hydrochloride in Treating Patients With Stage III Non-small Cell Lung Cancer

Extension of Phase 3 Gene Therapy for Painful Diabetic Neuropathy

A Phase 1/2 Study of CPI-0610 With and Without Ruxolitinib in Patients With Hematologic and Myeloproliferative Malignancies

A Study of Xevinapant (Debio 1143) in Combination With Platinum-Based Chemotherapy and Standard Fractionation Intensity-Modulated Radiotherapy in Participants With Locally Advanced Squamous Cell Carcinoma of the Head and Neck, Suitable for Definitive Chemoradiotherapy (TrilynX)

Study of Relacorilant in Combination With Nab-Paclitaxel for Patients With Recurrent Platinum-Resistant Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Natural History Evaluation of Charcot Marie Tooth Disease (CMT) Types CMT1B, CMT2A, CMT4A, CMT4C, and Others

Genetics of Charcot Marie Tooth (CMT) - Modifiers of CMT1A, New Causes of CMT2

Fractionated Docetaxel and Radium 223 in Metastatic Castration-Resistant Prostate Cancer

Post-Surgical Stereotactic Radiotherapy (SRT) Versus GammaTile-ROADS (Radiation One and Done Study)

SPI-62 as a Treatment for Adrenocorticotropic Hormone-dependent Cushing's Syndrome

Partial Breast Re-irradiation Using Ultra Hypofractionation (PRESERVE)

Open-label Extension Study of Enlicitide Decanoate (MK-0616/Enlicitide Oral PCSK9 Inhibitor) in Adults With Hypercholesterolemia (MK-0616-019) CORALreef Extension

Efficacy, Safety, and Tolerability of LPRI-CF113 as an Oral Contraceptive in Females

Frespaciguat (MK-5475) INSIGNIA-PH-COPD: A Study of the Efficacy and Safety of Frespaciguat (an Inhaled sGC Stimulator) in Adults With PH-COPD

A Study of Subcutaneous Nivolumab Versus Intravenous Nivolumab in Participants With Previously Treated Clear Cell Renal Cell Carcinoma That is Advanced or Has Spread

Study of Diagnostic Performance of [18F]CTT1057 for PSMA-positive Tumors Detection