Clinical Trials in Maryland

Showing 8101-8120 of 23,284 trials

Digital Therapeutic for Depression After Head Injury in Current and Former US Military Personnel

NCT05147506

The Center for Neuroscience and Regenerative Medicine (CNRM) Clinical Trials Unit has developed the first cognitive-behavioral therapy (CBT) digital therapeutic (DTx) mobile application to counteract depressive symptoms in military service members and veterans with a history of mild traumatic brain injury (mTBI). This trial will assess the efficacy of the novel CBT-DTx for depression following mTBI compared to an educational comparison DTx.

Depressive SymptomsMild Traumatic Brain Injury

Henry M. Jackson Foundation for the Advancement of Military Medicine113 participantsStarted Jun 2022

Bethesda, Maryland, United States

TERMINATEDPhase 1/217 miles

Study of TPX-0046, A RET/SRC Inhibitor in Adult Subjects With Advanced Solid Tumors Harboring RET Fusions or Mutations

NCT04161391

A phase 1/2, first-in-human, open-label study to determine the safety, tolerability, PK, and preliminary efficacy of the novel RET/SRC inhibitor TPX-0046 in adult subjects with advanced or metastatic solid tumors harboring RET mutations or alterations. The study consists of three portions: 1) Phase 1 Dose Escalation and Food Effect Sub-study, and 2) Phase 1 dose expansion and 3) Phase 2 efficacy evaluation.

Non Small Cell Lung CancerMedullary Thyroid CancerRET Gene Mutation+2 more

Turning Point Therapeutics, Inc.41 participantsStarted Dec 2019

La Jolla, California, United States • Orange, California, United States • Aurora, Colorado, United States +18 more locations

Digital Therapeutic for Depression After Head Injury in Current and Former US Military Personnel

Study of TPX-0046, A RET/SRC Inhibitor in Adult Subjects With Advanced Solid Tumors Harboring RET Fusions or Mutations

Find Trials by Condition in Maryland

Long-term Follow-Up Study of RGX-314 and Fellow Eye Substudy

A Study to Evaluate LB1148 for Return of Bowel Function in Subjects Undergoing Bowel Resection

Phase I Study of Cell Therapies for the Treatment of Patients With Relapsed or Refractory AML or High-risk MDS

A Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Miricorilant in Obese Adult Patients With Schizophrenia While Taking Antipsychotic Medications (GRATITUDE II)

Isatuximab in Combination With Cemiplimab in Relapsed/Refractory Multiple Myeloma (RRMM) Patients

Dapagliflozin at Discharge on Hospital Heart Failure Readmission

Tradipitant in Treatment-resistant Pruritus Associated With Atopic Dermatitis

Detecting Cancers Earlier Through Elective Plasma-based CancerSEEK Testing

House Dust Mite Allergy Trial In Children

Comparative Effectiveness of Biologics or Small Molecule Therapies in Inflammatory Bowel Disease (IBD)

Cryopreserved Human Umbilical Cord (TTAX01) for Late Stage, Complex Non-healing Diabetic Foot Ulcers (AMBULATE DFU)

Phase I Trial of 225Ac-J591 in Patients With mCRPC

A Study of TAK-981 Given With Rituximab in Adults With Relapsed or Refractory CD20-Positive Non-Hodgkin Lymphoma

Investigating Gains in Neurocognition in an Intervention Trial of Exercise

Efficacy and Safety of ALXN1840 Administered for 48 Weeks Versus Standard of Care in Participants With Wilson Disease

Study of ADCT-301 in Patients With Selected Advanced Solid Tumors

Effects of Dapagliflozin in Non-diabetic Patients With Proteinuria

A Study of Replagal in Treatment-naïve Adults With Fabry Disease