Clinical Trials in Maryland

Showing 7341-7360 of 23,284 trials

Pharmacokinetics and Pharmacogenomics of Ribociclib in Race-based Cohorts

NCT04657679

The aim is to determine the pharmacological and biochemical association between ribociclib exposure and CYP3A variants in African American/Blacks and Non-Hispanic White patients. The investigators hypothesize that patients treated with ribociclib who are CYP3A5 poor metabolizers may be exposed to higher levels of ribociclib than CYP3A5 intermediate or normal metabolizers. The findings could allow clinicians to tailor treatments to maintain therapeutic doses while limiting toxicities.

Breast Cancer

Georgetown University21 participantsStarted May 2021

Washington D.C., District of Columbia, United States • Washington D.C., District of Columbia, United States • Boston, Massachusetts, United States

TERMINATEDPhase 117 miles

PAK4 and NAMPT in Patients With Solid Malignancies or NHL (PANAMA)

NCT02702492

This study will evaluate the safety, tolerability, and efficacy of oral KPT-9274 for the treatment of patients with advanced solid malignancies or non-Hodgkin's lymphoma (NHL).

Solid TumorsNHL

Karyopharm Therapeutics Inc60 participantsStarted Jun 2016

Los Angeles, California, United States • Aurora, Colorado, United States • Washington D.C., District of Columbia, United States +5 more locations

Pharmacokinetics and Pharmacogenomics of Ribociclib in Race-based Cohorts

PAK4 and NAMPT in Patients With Solid Malignancies or NHL (PANAMA)

Find Trials by Condition in Maryland

Registry of Subjects With Drug Resistant Epilepsy and Treated With the VNS Therapy System.

Study to Evaluate the Efficacy, Safety, and Tolerability of Mirabegron in Older Adult Subjects With Overactive Bladder (OAB)

CGM/Clarity Use, Glycemic Control and Clinical Outcomes

Platelet Rich Plasma Versus Corticosteroids in Knee Osteoarthritis Pain

Phase 3 Study to Evaluate the Efficacy and Safety of Intravenous BIIB093 (Glibenclamide) for Severe Cerebral Edema Following Large Hemispheric Infarction

Navitoclax and Sorafenib Tosylate in Treating Patients With Relapsed or Refractory Solid Tumors

Glyburide Advantage in Malignant Edema and Stroke Pilot

Analysis of Both Sex and Device Specific Factors on Outcomes in Patients with Non-Ischemic Cardiomyopathy

A Phase 1/2 Trial of SP-101 for the Treatment of Cystic Fibrosis (CF)

A Study to Evaluate the Safety and Therapeutic Activity of GI-102 As a Single Agent and in Combination with Conventional Anti-cancer Drugs, Pembrolizumab or Trastuzumab Deruxtecan(T-DXd) in Patients with Advanced Solid Tumors (KEYNOTE-G08)

RCT of Brain Longitudinal Biomarker Study (OPT-Neuro RCT)

A Multi Center Study of Sexual Toxicities After Radiotherapy

First in Human Study of M1069 in Advanced Solid Tumors

Observational Study to Assess Migraine Prediction Tool

FPA150 in Patients With Advanced Solid Tumors

Real-World Evaluation of Eko Algorithms in a Point of Care Setting

Adjunctive Fosfomycin for Treatment of Staphylococcus Aureus Bacteraemia

SMART Africa (Strengthening Mental Health Research and Training)