Clinical Trials in Maryland

Showing 6841-6860 of 23,284 trials

Mapping the Phenotype in Adults With Phelan-McDermid Syndrome

NCT03426059

The protocol aims to comprehensively define the phenotype of Phelan-McDermid Syndrome and to identify potential genetic factors, which may play a role in the variability of the disease's outcomes. The first aim involves a physical exam, a neurological exam, collection of medical history information, a clinical genetic evaluation, blood work and neuropsychological assessments. If clinically indicated, the protocol collects information from medical tests. These medical tests may include electrocardiography, echocardiography, renal ultrasonography, and renal ultrasound.

Phelan-McDermid SyndromeAutism Spectrum DisorderIntellectual Disability

Boston Children's Hospital24 participantsStarted May 2018

Stanford, California, United States • Chicago, Illinois, United States • Bethesda, Maryland, United States +3 more locations

Active Not Recruiting17 miles

Mapping the Genotype, Phenotype, and Natural History of Phelan-McDermid Syndrome

NCT02461420

The purpose of this study is to comprehensively characterize PMS using standardized medical, cognitive, and behavioral measures and to track the natural history of the syndrome using repeated longitudinal assessments. In addition, this study will be aiming to identify biomarkers using neuroimaging, including diffusion tensor imaging and identify genetic factors which contribute to diverse phenotypes in patients with PMS.

Phelan-McDermid SyndromeAutism Spectrum DisorderIntellectual Disability

Boston Children's Hospital205 participantsStarted May 2015

Stanford, California, United States • Chicago, Illinois, United States • Bethesda, Maryland, United States +2 more locations

Mapping the Phenotype in Adults With Phelan-McDermid Syndrome

Mapping the Genotype, Phenotype, and Natural History of Phelan-McDermid Syndrome

Find Trials by Condition in Maryland

Low GI Diet in Children and Adolescents With ALL

A Phase 3 Randomized, Placebo-controlled Trial of Carboplatin and Paclitaxel With or Without Veliparib (ABT-888) in HER2-negative Metastatic or Locally Advanced Unresectable BRCA-associated Breast Cancer

BioProtect Balloon Implant™ Balloon System Pivotal Study BP-007

P-PSMA-101 CAR-T Cells in the Treatment of Subjects With Metastatic Castration-Resistant Prostate Cancer (mCRPC) and Advanced Salivary Gland Cancers (SGC)

A Study to Assess the Pharmacodynamics of VK0214 in Male Subjects With AMN

Evaluation of the Safety and Effectiveness of Bilateral Exablate Ablation of the Pallidothalamic Tract (PTT) for the Treatment of the Motor Complications of Parkinson's Disease (PD)

A Study of KB-0742 in Participants With Relapsed or Refractory Solid Tumors Including Platinum Resistant High Grade Serous Ovarian Cancer (HGSOC)

An Extension Study to Evaluate Maintenance of Efficacy and Long-term Treatment Effect of Oral Budesonide Suspension (OBS) in Adults and Adolescents With Eosinophilic Esophagitis (EoE)

A Study to Assess the Safety, Tolerability and Efficacy of IONIS-AGT-LRx in Hypertensive Participants With Uncontrolled Blood Pressure

A Study Evaluating Safety and Tolerability, and Pharmacokinetics of Navitoclax Monotherapy and in Combination With Ruxolitinib in Participants With Myeloproliferative Neoplasm

Study of Daily Application of Nestorone® (NES) and Testosterone (T) Combination Gel for Male Contraception

Safety and Effectiveness of the MiniMed™ 780G System With DS5 CGM

Neuroblastoma Precision Trial

RAD001 and Neurocognition in PTEN Hamartoma Tumor Syndrome

A Phase 1b Study of Imvotamab in Moderate to Severe Rheumatoid Arthritis

Interventional Study of INCB 99280 With Ipilimumab in Participants With Select Solid Tumors

A Study to Learn How Well the Study Treatment Zabedosertib (BAY1834845) Works and How Safe it is Compared to Placebo in Adult Participants With Moderate-to-severe Atopic Dermatitis

MCT for the Harvard/UCSF ROBIN Center