Clinical Trials in Los Angeles

Showing 5721-5740 of 16,901 trials

The CAPTURE Study: Validating a Unique COPD Case Finding Tool in Primary Care (Aim 3)

NCT03583099

A prospective, multicenter study including a cross-section validation to define sensitivity and specificity of CAPTURE to identify previously undiagnosed patients with clinically significant Chronic Obstructive Pulmonary Disease (COPD), and its impact on clinical care across a broad range of primary care settings in a cluster randomized controlled clinical trial.

Chronic Obstructive Pulmonary Disease (COPD)

Weill Medical College of Cornell University2,004 participantsStarted Oct 2018

Los Angeles, California, United States • Aurora, Colorado, United States • Miami, Florida, United States +6 more locations

COMPLETEDNA< 1 mile

Using Behavioral Economics to Reduce Low-Value Care

NCT04104256

There is strong consensus - based on robust randomized trial data - that routine pre-operative (pre-op) testing for cataract surgery is inappropriate. Despite these widely endorsed evidence-based recommendations, most seniors undergoing cataract surgery still receive unnecessary blood testing, EKGs, and chest X-rays (CXRs); another substantial percentage even undergo nonindicated cardiac stress tests. We will integrate three new best practice alert (BPA) nudges into the University of California, Los Angeles (UCLA) Health electronic health record (EHR). The nudges are informed by behavioral economic theory and are designed to alter the choice architecture for physicians to decrease the rate of pre-op test ordering while still preserving clinician autonomy. We will conduct a pragmatic trial to evaluate whether these BPA nudges reduce low-value pre-op testing for cataract surgery.

Pre-Operative Testing for Cataract Surgery

University of California, Los Angeles1,045 participantsStarted Jun 2021

Los Angeles, California, United States

The CAPTURE Study: Validating a Unique COPD Case Finding Tool in Primary Care (Aim 3)

Using Behavioral Economics to Reduce Low-Value Care

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PARP Inhibition for Triple Negative Breast Cancer (ER-/PR-/HER2-)With BRCA1/2 Mutations

Study to Evaluate the Safety and Efficacy of CSB-001 Ophthalmic Solution 0.1% in Neurotrophic Keratitis Subjects

An Electronic Clinical Decision Support Tool to Reduce Low-value Antipsychotic Prescriptions

Evaluating the Response of the Immune System of People with Long COVID (post SARS-CoV-2)

Neuroplasticity in TBI and Schizophrenia

A Study of Sotatercept for the Treatment of Pulmonary Arterial Hypertension (MK-7962-003/A011-11)(STELLAR)

SPT for Sensitization of Collagen Dressing

Open-label Extension Study in Patients 65 Years or Older With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

A Phase 2 Study to Evaluate the Efficacy and Safety of VIR-2482 for the Prevention of Illness Due to Influenza A

Open-Label, Phase 1 Study to Evaluate Duration of Severe Neutropenia After Same-Day Dosing of Eflapegrastim in Patients With Breast-Cancer

A Study to Evaluate Treatment Satisfaction With Erenumab in Participants With Migraine

Pharmacokinetics and Pharmacodynamics of Rifaximin Novel Formulations in Patients With Sickle Cell Disease

Study of Daxdilimab (HZN-7734) for the Treatment of Systemic Lupus Erythematosus in an Open-label Extension Study

Breast Cancer Index (BCI) Registry

2021 PMT iAge® Intervention Trial by Edifice Health

A Study of CC-95251, a Monoclonal Antibody Directed Against SIRPα, in Participants With Advanced Solid and Hematologic Cancers

A Drug-Drug Interaction Study to Evaluate the Effect of Ripretinib on the Pharmacokinetics of a CYP2C8 Probe Substrate in Patients with Advanced GIST

Engaging Staff to Improve COVID-19 Vaccination Response at Long-Term Care Facilities