Clinical Trials in Los Angeles

Showing 3421-3440 of 16,901 trials

Neurophysiologic Biomarkers in Rett Syndrome

NCT05932589

The goal of this observational study is to identify candidate biomarkers in individuals with Rett Syndrome (RTT). The main questions it aims to answer are: * Do these biomarkers change during clinical changes in individuals with RTT? * Are biomarkers stable over time in clinically stable individuals? * Do these biomarkers correlate with severity of RTT? Participants will be asked to undergo an electroencephalogram (EEG) with measurements of Evoked Potentials (EP) to measure electrical activity in the brain. Researchers will compare findings in individuals with RTT to those in typically developing individuals to see if there are differences between the two groups.

Rett SyndromeRTTRett Syndrome, Atypical

Children's Hospital of Philadelphia202 participantsStarted Oct 2023

Los Angeles, California, United States • Aurora, Colorado, United States • Brookline, Massachusetts, United States +3 more locations

RECRUITINGPhase 1< 1 mile

Ziftomenib in Combination With Chemotherapy for Children With Relapsed/Refractory Acute Leukemia

NCT06376162

The primary objective of the study is to determine the recommended phase 2 dose (RP2D) of ziftomenib in combination with chemotherapy (FLA) in children with relapsed or refractory KMT2A-r, NUP98-r, or NPM1-m acute leukemia based on safety and pharmacokinetics (PK).

Relapsed/Refractory KMT2A-r Acute LeukemiaRelapsed/Refractory NUP98-r Acute LeukemiaRelapsed/Refractory NPM1-m Acute Leukemia

PedAL BCU, LLC20 participantsStarted Mar 2025

Los Angeles, California, United States • Aurora, Colorado, United States • Atlanta, Georgia, United States +17 more locations

Neurophysiologic Biomarkers in Rett Syndrome

Ziftomenib in Combination With Chemotherapy for Children With Relapsed/Refractory Acute Leukemia

Find Trials by Condition in Los Angeles

Open-label Long-term Study of Adjunctive Brivaracetam in Pediatric Subjects With Epilepsy

PRV-015 in Gluten-free Diet Non-responsive Celiac Disease

IN.PACT™ AV Access Post-Approval Study (PAS002)

A Study of Zolbetuximab (IMAB362) in Adults With Gastric Cancer

A Single-ascending Dose (Part A) and Repeat-dose (Part B) Study to Investigate the Safety, Pharmacokinetics and Efficacy (Part B Only) of UCB1381 in Healthy Study Participants (Part A) and in Study Participants With Moderate to Severe Atopic Dermatitis (Part B)

Opioids and Social Support Enhanced Extinction Effects

IBRX-042 In Participants With HPV-Associated Tumors

A Phase 2, Open-label, Single-arm Study Of Autologous M-CENK Adoptive Cell Therapy And N-803 (IL-15 Superagonist) In Combination With Gemcitabine In Participants With Recurrent Platinum-Resistant High-Grade Ovarian Cancer

An Open Label Study Evaluating the Efficacy and Safety of Etrumadenant (AB928) Based Treatment Combinations in Participants With Metastatic Colorectal Cancer.

Personalized Therapy Study - Intrinsic Antitachycardia Pacing Post-Approval Study (iATP PAS)

GRAVITAS-309: Itacitinib and Corticosteroids as Initial Treatment for Chronic Graft-Versus-Host Disease

A Phase 1 Study of ZL-1218 in Subjects With Advanced Solid Tumors

A Study to Investigate the Antiviral Effect, Safety, Tolerability and Pharmacokinetics of VH3739937 in in Treatment-Naive Adults Living With HIV-1

A Prospective Registry to Enable Collection of Standardized Routine Care Oncology Patient Data

Inappropriate Sinus Tachycardia Registry

Parametric Response Mapping (PRM) for the Detection of Chronic Lung Injury in Hematopoietic Cell Transplant Recipients

Prospective Healthcare-Associated Links in Transmission of Nontuberculous Mycobacteria

Staphylococcus Aureus Network Adaptive Platform Trial