Clinical Trials in Los Angeles

Showing 321-340 of 14,465 trials

Evaluation of PK, PD, Efficacy, Safety, and Immunogenicity of IV Ravulizumab in Pediatric Participants With Generalized Myasthenia Gravis

NCT05644561

The primary purpose of this study is to characterize the pharmacokinetics and pharmacodynamics of treatment with ravulizumab intravenous infusion in pediatric participants with gMG.

Generalized Myasthenia GravisgMG

Alexion Pharmaceuticals, Inc.12 participantsStarted Jun 2023

Los Angeles, California, United States • Boston, Massachusetts, United States • Chapel Hill, North Carolina, United States +8 more locations

RECRUITINGPhase 3< 1 mile

A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

NCT07174336

The purpose of the study is to assess the efficacy and safety of the addition of Tersolisib (LY4064809/STX-478) to other anti-cancer drugs as first treatment for advanced hormone receptor-positive (HR+)/human epidermal growth factor receptor 2-negative (HER2-) breast cancer. Participants can remain in the study as long as the drug is helping the cancer without unbearable side effects.

Breast NeoplasmsNeoplasm Metastasis

Eli Lilly and Company920 participantsStarted Dec 2025

Anchorage, Alaska, United States • Chandler, Arizona, United States • Phoenix, Arizona, United States +314 more locations

Evaluation of PK, PD, Efficacy, Safety, and Immunogenicity of IV Ravulizumab in Pediatric Participants With Generalized Myasthenia Gravis

A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

Find Trials by Condition in Los Angeles

A Clinical Study of MK-2214 in People With Early Alzheimer's Disease (MK-2214-004)

A Study of LY4584180 in Adult Participants With Previously Treated Blood Cancers

Study of Sparsentan in Patients With Primary Focal Segmental Glomerulosclerosis (FSGS)

A Study to See How Well Lebrikizumab Works in Adults and Adolescents With Moderate Atopic Dermatitis (Eczema) and High Itch Burden

A Study of Selpercatinib (LOXO-292) in Participants With Advanced Solid Tumors, RET Fusion-Positive Solid Tumors, and Medullary Thyroid Cancer (LIBRETTO-001)

ONC201 in H3 K27M-mutant Diffuse Glioma Following Radiotherapy (the ACTION Study)

A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)

A Study of KIVU-107 in Participants With Locally Advanced or Metastatic Solid Tumors

Testing the Addition of Pedmark to Cisplatin Chemotherapy for Reducing Drug-Induced Ear Damage in Men With Stage II-III Metastatic Testicular Germ Cell Tumors

A Study of CX11 Tablets in Patients With Type 2 Diabetes Mellitus

Comparison of Uncomplicated Candidemia Therapy Duration in Children

Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer After Failure of EGFR TKI Therapy (IZABRIGHT-Lung01)

Tapinarof for the Treatment of Plaque Psoriasis in Pediatric Subjects

Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer

Treat & Extend Versus Fixed Dosing With Faricimab for Management of Diabetic Macular Edema: A Pragmatic, Multi-center, Open-label, Randomized, Controlled Trial

MMA Embolization for Refractory Chronic Migraine

Study of Osimertinib With and Without Ramucirumab in Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

A Study of Baricitinib (LY3009104) for the Delay of Stage 3 Type 1 Diabetes in At-Risk Children and Adults