Clinical Trials in Los Angeles

Showing 2821-2840 of 14,465 trials

Nafamostat Efficacy in Phase 3 Registrational CRRT Study

NCT06150742

A prospective, randomized, placebo-controlled clinical study to investigate the safety and efficacy of Niyad (nafamostat mesylate) for anticoagulation of extracorporeal blood circulating through a dialysis filter in patients undergoing CRRT who cannot tolerate heparin or are at higher risk for bleeding.

Acute Kidney Injury

Talphera, Inc70 participantsStarted Aug 2024

Los Angeles, California, United States • Orlando, Florida, United States • Detroit, Michigan, United States +7 more locations

SUSPENDED< 1 mile

Longitudinal Study of Mitochondrial Hepatopathies

NCT01148550

The specific aims of this study are (1) to determine the clinical phenotypes and natural history of hepatic RC and FAO disorders, (2) to determine the correlation between genotype and phenotype, (3) to determine if circulating biomarkers reflect diagnosis and predict liver disease progression and survival with the native liver, (4) to determine the clinical outcome of these disorders following liver transplantation, and (5) to develop a repository of serum, plasma, urine, tissue and DNA specimens that will be used in ancillary studies. To accomplish these aims, the ChiLDReN investigators at clinical sites (currently 9 sites) will prospectively collect defined data and specimens in a uniform fashion at fixed intervals in a relatively large number of subjects. Clinical information collected from subjects and their parents will enhance the potential for meaningful research in these disorders. A biobank of previously collected subject specimens and DNA samples will be established for use in ancillary studies to be performed in addition to this study.

Acute Liver FailureMitochondrial DiseasesEnd Stage Liver Disease+2 more

Arbor Research Collaborative for Health90 participantsStarted Aug 2010

Los Angeles, California, United States • San Francisco, California, United States • Aurora, Colorado, United States +13 more locations

Nafamostat Efficacy in Phase 3 Registrational CRRT Study

Longitudinal Study of Mitochondrial Hepatopathies

Find Trials by Condition in Los Angeles

Validation of Early Prognostic Data for Recovery Outcome After Stroke for Future, Higher Yield Trials

A Study of LY3972406 in Adult Participants With Moderate-to-Severe Plaque Psoriasis

Biliary Atresia Study in Infants and Children

CemiplimAb Survivorship Epidemiology

ALTUS: Performance of a Multi- Target Hepatocellular Carcinoma (HCC) Test in Subjects With Increased Risk

Open-Label Safety Study of Acoramidis (AG10) in Symptomatic ATTR Participants

A Clinical Trial to Evaluate the Safety and Immunogenicity of BG505 MD39.3, BG505 MD39.3 gp151, and BG505 MD39.3 gp151 CD4KO HIV Trimer mRNA Vaccines in Healthy, HIV-uninfected Adult Participants

Efficacy and Safety of Patidegib Gel 2% for Preventing Basal Cell Carcinomas on the Face of Adults With Gorlin Syndrome

Effectiveness and Safety Study of Tezepelumab in Adults & Adolescent Participants With Severe Asthma in the United States

Study of EYP-1901 in Subjects With Wet Age Related Macular Degeneration (wAMD)

Safety and Tolerability of RPE Stem Cell-derived RPE(RPESC-RPE) Transplantation in Patients With Dry Age-related Macular Degeneration (AMD)

A Study of ASP-1929 Photoimmunotherapy in Combination With Pembrolizumab in First-line Treatment of Locoregional Recurrent Squamous Cell Carcinoma of the Head and Neck With No Distant Metastases

Phase 1b/2a Randomized Double-blind Study to Investigate Safety Tolerability PK PD Preliminary Efficacy of Oral Administration of SNIPR001 in Patients With Hematologic Malignancy Scheduled for Allogeneic Hematopoietic Stem-Cell Transplant Receiving FQ Prophylaxis & Harboring FQR Ecoli Pre-Transplant

Study of JANX008 in Subjects With Advanced or Metastatic Solid Tumor Malignancies

Genetically Engineered Natural Killer (NK) Cells With or Without Atezolizumab for the Treatment of Non-small Cell Lung Cancer Previously Treated With PD-1 and/or PD-L1 Immune Checkpoint Inhibitors

Study to Investigate the Effect of Hepatic Impairment on the Pharmacokinetics, Safety, and Tolerability of AZD5004

An Extension Study to Learn About the Long-Term Safety of Fazirsiran and if Fazirsiran Can Help People With Alpha-1 Antitrypsin Liver Disease

A Study of Inhaled AZD8630 in Adolescents With Asthma