Clinical Trials in Los Angeles

Showing 2321-2340 of 14,465 trials

VIRTUUS Children's Study

NCT03719339

The objective of the VIRTUUS Children's Study is to adapt identified and validated adult noninvasive diagnostic and prognostic biomarkers for the characterization of allograft status in pediatric recipients of kidney allografts.

Renal Transplant RejectionPediatric Kidney DiseaseEnd Stage Renal Disease+4 more

Children's Hospital of Philadelphia445 participantsStarted Aug 2017

La Jolla, California, United States • Los Angeles, California, United States • Los Angeles, California, United States +10 more locations

TERMINATEDPhase 2< 1 mile

A Trial to Evaluate the Efficacy and Safety of PQ912 in Patients With Early AD

NCT03919162

This is a Phase 2A multi-center, randomized, double blind, placebo-controlled, parallel group study of varoglutamstat, with a stage gate to Phase 2B. In Phase 2A there will be adaptive dosing evaluation of three dose levels with exposure to varoglutamstat or placebo for a minimum of 24 weeks, with preliminary evaluation of both cognitive function and pharmacodynamic changes on EEG spectral analysis in approximately 180 participants. In the event that the stage gate for Phase 2B is reached, then Phase 2B will assesses efficacy and longer-term safety in a larger study group, i.e., 414.

Alzheimer Disease

Vivoryon Therapeutics N.V.112 participantsStarted Nov 2021

Phoenix, Arizona, United States • Sun City, Arizona, United States • Chula Vista, California, United States +19 more locations

VIRTUUS Children's Study

A Trial to Evaluate the Efficacy and Safety of PQ912 in Patients With Early AD

Find Trials by Condition in Los Angeles

Safely Optimizing Body Weight With TCMCB07 in Patients With Newly Diagnosed Metastatic Colorectal Cancer Undergoing Chemotherapy

A Study to Evaluate Safety, Tolerability and Pharmacokinetics of Two Different Doses of Alpha1-Proteinase Inhibitor Subcutaneous (Human) 15% in Participants With Alpha1-Antitrypsin Deficiency

Study of Cabozantinib in Combination With Atezolizumab Versus Sorafenib in Participants With Advanced Hepatocellular Carcinoma (HCC) Who Have Not Received Previous Systemic Anticancer Therapy

ACP-196 (Acalabrutinib) in Combination With Pembrolizumab, for Treatment of Hematologic Malignancies

A Phase 2, Dose Ranging Study Assessing Rocatinlimab in Moderate-to-severe Asthma

A Study of Zigakibart in Adults With IgA Nephropathy

A Clinical Study That Will Evaluate How Well SEP-363856 Works and How Safe it is in People With Schizophrenia That Switch to SEP-363856 From Their Current Antipsychotic Medication

ADCT-602 in Treating Patients With Recurrent or Refractory B-cell Acute Lymphoblastic Leukemia

Quick Measure Study for iCare ST500 and iCare IC200

A Phase 2 Study to Evaluate the Efficacy and Safety of SAR444656 Compared With Placebo in Adult Participants With Moderate to Severe Hidradenitis Suppurativa

A Study of the Genetic Basis of Response to Growth Hormone Treatment in Children With Idiopathic Short Stature

A Study of Olezarsen (Formerly Known as AKCEA-APOCIII-LRX) Administered to Adults With Familial Chylomicronemia Syndrome (FCS) Previously Treated With Volanesorsen

Extension Study to Evaluate Safety and Tolerability of Oral Dersimelagon (MT-7117) in Subjects With Erythropoietic Protoporphyria (EPP) or X-Linked Protoporphyria (XLP)

A Research Study to Look at How Well CagriSema Helps People Living With Obesity Lose Weight and Maintain Weight Loss in the Long-term

UNITY VCS Vitreoretinal Surgery

A Study of HBS-201 (Pitolisant Delayed-release)

Ganciclovir to Prevent Reactivation of Cytomegalovirus in Patients With Acute Respiratory Failure and Sepsis

An Open-label Extension Trial of CVL-865 as Adjunctive Therapy in the Treatment of Focal Onset Seizures