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Discover 19,692 clinical trials near Illinois. Find research studies in your area.
Showing 17321-17340 of 19,692 trials
NCT00945477
A growing body of literature supports the role of angiogenesis in the development and spread of a variety of human cancers including prostate cancer. * Vascular endothelial growth factor (VEGF) expression is low in normal prostate tissue, but markedly increased in tumor tissues, and has a positive association with tumor stage and grade * Plasma VEGF levels are significantly elevated in patients with hormone refractory prostate cancer (HRPC) compared to those patients with localized disease and have been associated with disease progression in other cancer patient population. * The Cancer and Leukemic Group-B demonstrated that VEGF levels correlate with survival. Pazopanib is a potent multi-target receptor tyrosine kinase inhibitor of vascular endothelial growth factor receptors.
NCT00002577
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. PURPOSE: Phase I/II trial to study the effectiveness of radiation therapy in treating patients with non-small cell lung cancer that cannot be surgically removed.