Clinical Trials in Illinois

Showing 10861-10880 of 19,692 trials

Docetaxel/Prednisone Versus Docetaxel/Prednisone and Enzalutamide in Castration-Resistant Prostate Cancer

NCT02685267

This is a prospective randomized phase II clinical trial where patients who are receiving enzalutamide in the pre-chemotherapy space are randomized upon objective progression (radiographic and/or clinical per PCWG2 criteria) to docetaxel/prednisone alone or the same combination plus enzalutamide. The primary aim is to evaluate whether continuing enzalutamide in combination with docetaxel in patients who failed or progressed while on enzalutamide would increase progression-free survival (PFS) by 4 months. The secondary end points are PSA responses, percent of patients alive at 1 and 2 years, decline in circulating tumor cells (CTCs), and quality of life (QOL) using validated scales.

Prostate Cancer

Prostate Cancer Clinical Trials Consortium9 participantsStarted Feb 2016

Chicago, Illinois, United States • Decatur, Illinois, United States • Evanston, Illinois, United States +2 more locations

TERMINATEDPhase 2125 miles

A Phase II Study of M2951 in SLE

NCT02975336

M2951 is an investigational drug under evaluation for treatment of autoimmune and inflammatory disorders. The purpose of the study was to assess the Safety and Efficacy of M2951 in participants with Systemic Lupus Erythematosus (SLE).

Systemic Lupus Erythematosus

EMD Serono Research & Development Institute, Inc.469 participantsStarted Jan 2017

Anniston, Alabama, United States • Mesa, Arizona, United States • Phoenix, Arizona, United States +154 more locations

Docetaxel/Prednisone Versus Docetaxel/Prednisone and Enzalutamide in Castration-Resistant Prostate Cancer

A Phase II Study of M2951 in SLE

Find Trials by Condition in Illinois

A Study to Evaluate Next-Dose Transition From Zolpidem to Lemborexant (LEM) for the Treatment of Insomnia

A Safety, Efficacy and Pharmacokinetics Study of CD11301 for the Treatment of Cutaneous T-Cell Lymphoma (CTCL)

Rheos System for the Treatment of HFpEF Heart Failure

Clinical Study to Evaluate the Maximum Tolerated Dose of BAY1000394 When Given Together With Chemotherapy and the Effectiveness of This Combination Treatment in Shrinking a Specific Type of Lung Tumors (Small Cell Lung Cancer)

Dose-Escalation Study Of Palbociclib + Nab-Paclitaxel In mPDAC

ARQ 197 for Participants With Relapsed or Refractory Germ Cell Tumors

A Study of ALKS 5461 for Treatment Refractory Major Depressive Disorder (MDD)

Afrezza Safety and Pharmacokinetics Study in Pediatric Patients

ZK-Epo Given With Carboplatin in Patients With Recurrent Ovarian Cancer

Essure (Model ESS310) Placement Rate Study

A Clinical Proof-of-principle Trial in Adult Subjects With Newly Diagnosed Type 1 Diabetes Mellitus Investigating the Effect of NNC0114-0006 and Liraglutide on Preservation of Beta-cell Function

Peer Led Asthma Self Management for Adolescents: PLASMA

Ultra-Low Tidal Volume Mechanical Ventilation in ARDS Through ECMO

Wide Frequency Band Test of Hearing in Veterans

Bedside Optical Retinal Assessment of Hypoxic Ischemic Encephalopathy in Infants

Cytoreductive Prostatectomy in Treating Patients With Newly Diagnosed, Metastatic Prostate Cancer

Tisotumab Vedotin (HuMax®-TF-ADC) Safety Study in Patients With Solid Tumors

Study of CAD-1883 for Spinocerebellar Ataxia