Clinical Trials in Illinois

Showing 3001-3020 of 16,913 trials

A Pilot Study to Assess Safety and Efficacy of SIR1-365 in Patients With Severe COVID-19

NCT04622332

Primary Objective: • To evaluate overall safety and tolerability of SIR1-365 in patients with severe COVID-19 Secondary Objectives: * To assess the clinical efficacy of SIR1-365 in patients with severe COVID-19 * To assess the effects of SIR1-365 on multiple inflammatory biomarker levels including C-reactive protein (CRP), ferritin, lymphocyte and neutrophil counts, cytokines, and chemokines * To assess the effects of SIR1-365 on biomarkers indicative of target engagement in patients with severe COVID-19 * To assess the effects of SIR1-365 on biomarkers indicative of kidney injury in patients with severe COVID-19 * To assess the effects of SIR1-365 on biomarkers indicative of cardiovascular endothelial cell damage in patients with severe COVID-19 * To characterize plasma pharmacokinetics (PK) of SIR1-365 in patients with severe COVID-19

Corona Virus Infection

Sironax USA, Inc.45 participantsStarted Dec 2020

West Palm Beach, Florida, United States • Peoria, Illinois, United States • Jackson, Mississippi, United States +6 more locations

Active Not Recruiting44 miles

STOP Persistent AF PAS

NCT05005949

The STOP Persistent AF Post Approval Study (PAS) is a prospective, global, multicenter, observational trial.

Persistent Atrial Fibrillation

Medtronic Cardiac Ablation Solutions400 participantsStarted Aug 2021

Hartford, Connecticut, United States • Stamford, Connecticut, United States • Clearwater, Florida, United States +14 more locations

A Pilot Study to Assess Safety and Efficacy of SIR1-365 in Patients With Severe COVID-19

STOP Persistent AF PAS

Find Trials by Condition in Illinois

Trametinib in Treating Patients With Recurrent or Progressive Low-Grade Ovarian Cancer or Peritoneal Cavity Cancer

A Study to Evaluate the Efficacy and Safety of AVTX-009 in Patients With Moderate to Severe Hidradenitis Suppurativa

The PEERLESS Study

Study of LAU-7b for the Treatment of Coronavirus Disease 2019 (COVID-19) Disease in Adults

Study of COPD Subgroups and Biomarkers

Functional Lumen Opening With Self-Forming Magnetic Anastomosis

Integrity Implant System Post Market Clinical Follow-Up Study

Safety and Efficacy of NMD670 in Adult Patients With Type 1 and Type 2 Charcot-Marie-Tooth Disease

A Study to Assess the Long-term Efficacy and Safety of AXS-12 (Reboxetine) in Subjects With Narcolepsy (ENCORE)

HSCT for Patients With Fanconi Anemia Using Risk-Adjusted Chemotherapy

Selpercatinib Before Surgery for the Treatment of RET-Altered Thyroid Cancer

PROMIS and Mobility Evaluation in Sarcoma Patients

Abemaciclib in Treating Patients With Surgically Resectable, Chemotherapy Resistant, Triple Negative Breast Cancer

A Study to Learn About Ritlecitinib for the Potential Treatment of Chronic Spontaneous Urticaria in Adults.

A Clinical and Molecular Risk-Directed Therapy for Newly Diagnosed Medulloblastoma

B-PaLMZ for TB Meningitis

Study Evaluating INS018_055 Administered Orally to Subjects With Idiopathic Pulmonary Fibrosis

Cognitive Reserve and Response to Speech-Language Intervention in Bilingual Speakers With Primary Progressive Aphasia