Clinical Trials in Houston

Showing 1161-1180 of 15,366 trials

Pembrolizumab and Concurrent Chemoradiotherapy or Radiation Therapy in Treating Patients With Small Cell Lung Cancer

NCT02402920

This phase I trial studies the side effects and best dose of pembrolizumab when given together with chemoradiotherapy or radiation therapy in treating patients with small cell lung cancer. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Radiation therapy uses high energy x-rays to kill cancer cells and shrink tumors. Giving chemotherapy with radiation therapy may kill more cancer cells. Giving pembrolizumab with chemoradiotherapy or radiation therapy may be a better treatment for small cell lung cancer.

Extensive Stage Small Cell Lung CarcinomaLimited Stage Small Cell Lung CarcinomaNeuroendocrine Neoplasm

M.D. Anderson Cancer Center83 participantsStarted Jul 2015

Houston, Texas, United States

RECRUITINGNA< 1 mile

Streamlined Treatment of Pulmonary Exacerbations in Pediatrics

NCT06654752

The STOP PEDS RCT is a multicenter, parallel, open label randomized controlled trial evaluating the long-term (one year) and short-term safety and efficacy of two antibiotic treatment strategies for the management of outpatient pulmonary exacerbations (PEx) in the pediatric CF population.

Cystic Fibrosis

University of Washington, the Collaborative Health Studies Coordinating Center430 participantsStarted Dec 2024

Birmingham, Alabama, United States • Tucson, Arizona, United States • Los Angeles, California, United States +30 more locations

Pembrolizumab and Concurrent Chemoradiotherapy or Radiation Therapy in Treating Patients With Small Cell Lung Cancer

Streamlined Treatment of Pulmonary Exacerbations in Pediatrics

Find Trials by Condition in Houston

Study to Evaluate the Pharmacokinetics and Safety of Oral Decitabine and Cedazuridine in Cancer Patients With Hepatic Impairment

Study to Evaluate the Effect of GBT440 on TCD in Pediatrics With Sickle Cell Disease

A Study to Investigate Safety and Effectiveness of CRN09682 in Participants With SST2-Expressing NENs and Other Solid Tumors

Safety and Outcomes of MUSE Stem Cell Therapy in Individuals With Traumatic Brain Injury

Phase 1-2 Study of Low Dose ASTX727 (ASTX727 LD) in Lower Risk MDS

Sleep and Physical Activity in Patient and Caregiver Dyads Following Allogeneic Hematopoietic Cell Transplantation

Pembrolizumab (MK-3475) Versus Placebo Following Surgery and Radiation in Participants With Locally Advanced Cutaneous Squamous Cell Carcinoma (MK-3475-630/KEYNOTE-630)

Study to Evaluate the Pharmacokinetics and Safety of Oral Decitabine and Cedazuridine in Cancer Patients With Renal Impairment

A Study of Lasmiditan (LY573144) Treatment in Children Aged 6 to 17 With Migraine

Long-term Safety and Efficacy Evaluation of Lunsekimig in Adult Participants With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) Who Completed a Previous Lunsekimig CRSwNP Study

Long-Term Safety Study of Deucravacitinib Versus Ustekinumab in Participants With Psoriasis (PRAGMATYK)

Efficacy and Safety of Tildrakizumab Compared to Placebo in Anti-TNF naïve Subjects With Active Psoriatic Arthritis II (INSPIRE 2)

Advancing Cath Lab Results With FFRangio Coronary Physiology Assessment

A Varegacestat Hepatic Impairment Study

A Global Prospective Observational Registry of Patients With Pompe Disease

Antibiotic Cement Bead Pouch Versus Negative Pressure Wound Therapy

Phase II Randomized Trial of the Combination of Cetuximab and Sorafenib or Single Agent Cetuximab

STRatIfication of Vulvar SCC by HPV and p53 Status to Guide Excision