Clinical Trials in Houston

Showing 10381-10400 of 17,885 trials

Alvocidib in Combination With Decitabine and Venetoclax in Patients With Relapsed or Refractory AML or as Frontline Therapy in Unfit Patients With AML

NCT04493099

This phase I/II trial investigates the side effects and best dose of alvocidib when given together with decitabine and venetoclax and to see how well it works in treating patients with acute myeloid leukemia that has come back (relapsed), has not responded to previous treatment (refractory), or as frontline treatment for patients unable to receive other therapies (unfit). Alvocidib, decitabine, and venetoclax may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth.

Recurrent Acute Myeloid LeukemiaRefractory Acute Myeloid Leukemia

M.D. Anderson Cancer CenterStarted Oct 2020

Houston, Texas, United States

WITHDRAWNPhase 2< 1 mile

A Phase II Single-arm Intervention Trial of Nelfinavir in Patients With Grade 2/3 or 3 Cervical Intraepithelial Neoplasia

NCT01925378

Preliminary data showed that Nelfinavir has selective apoptotic effects on HPV+ cervical tumor cell lines. Furthermore, in a Phase I clinical trial, the combination of NFV and chemoradiotherapy showed acceptable toxicity and promising activity in patients with pancreatic cancer. Therefore, for the proposed research, the principal investigator will use a single-arm Phase II intervention trial study design with focus on the efficacy of NFV to induce complete or partial remission of CIN 2/3 or CIN 3 as well as biomarker evaluation.

Cervical Dysplasia

The University of Texas Health Science Center, HoustonStarted Nov 2018

Houston, Texas, United States

COMPLETED< 1 mile

Bone Mineral Density in Women With Uterine Fibroids or Endometriosis

NCT03744507

The purpose of this study is to characterize the longitudinal bone mineral density (BMD) in premenopausal women with uterine fibroids or endometriosis.

Uterine FibroidEndometriosis

Myovant Sciences GmbH660 participantsStarted Aug 2018

Mobile, Alabama, United States • Mesa, Arizona, United States • Huntington Beach, California, United States +60 more locations

Alvocidib in Combination With Decitabine and Venetoclax in Patients With Relapsed or Refractory AML or as Frontline Therapy in Unfit Patients With AML

A Phase II Single-arm Intervention Trial of Nelfinavir in Patients With Grade 2/3 or 3 Cervical Intraepithelial Neoplasia

Bone Mineral Density in Women With Uterine Fibroids or Endometriosis

Find Trials by Condition in Houston

GreenLight XPS Laser System Retrospective Chart Review

Epidural Blood Patch on the Resolution of Postdural Puncture Headache (PDPH)

Antibody Secreting Cell and Cyotokine Profiles in Neonates on ECMO

Gemcitabine Pharmacokinetics After Preoperative Chemoradiation Therapy

Study of the Effects of Education on Patients With Chronic Obstructive Pulmonary Disease

Telephone Counseling and Numberless Scales to Overcome Barriers to Adolescent Weight Loss

Effect of Whey Protein Hydrolysate on Human Muscle Protein Synthesis

Effect of In-Patient Exercise Training on Length of Hospitalization in Burned Patients

Safety and Tolerability Study for Age-Related Macular Degeneration

Effect of GTx-024 on Muscle Wasting in Patients With Non-Small Cell Lung Cancer (NSCLC) on First Line Platinum

First-in-Human Study of JNJ-74699157 in Participants With Tumors Harboring the KRAS G12C Mutation

DYSPORT™ Clinical & Health Economics Outcomes Registry in Cervical Dystonia

Phase IV-Cervical Dystonia-INTEREST IN CD2

Study of an Investigational Drug, RO7239361 (BMS-986089), in Ambulatory Boys With DMD

To Document the Effectiveness of BoNT-A Injection in Adult Subjects With Upper Limb Spasticity Following Stroke

Cefiderocol Concentrations in the Lungs of Hospitalized Patients With Bacterial Pneumonia

Quality of Life in Patients With Congenital Afibrinogenemia