Clinical Trials in Houston

Showing 10221-10240 of 17,885 trials

A Study of Oral LBH589 in Adult Patients With Advanced Hematological Malignancies

NCT00621244

This study evaluated safety, tolerability, pharmacokinetics and preliminary anti-leukemic or anti-tumor activity of LBH589B in adult patients with advanced hematological malignancies

LymphomaLeukemiaMultiple Myeloma

Novartis Pharmaceuticals175 participantsStarted Mar 2003

Augusta, Georgia, United States • Boston, Massachusetts, United States • Houston, Texas, United States +4 more locations

COMPLETEDPhase 4< 1 mile

Study of Effects of Sacubitril/Valsartan vs. Enalapril on Aortic Stiffness in Patients With Mild to Moderate HF With Reduced Ejection Fraction

NCT02874794

To determine whether treatment with sacubitril/valsartan provides a superior effect on aortic characteristic impedance compared to enalapril in patients with heart failure and reduced ejection fraction (left ventricular ejection fraction \[LVEF\] ≤ 40%) after 12 weeks of treatment. The primary endpoint is the change in aortic characteristic impedance (Zc = dP/dQ in early systole) between baseline and Week 12.

Heart Failure and Reduced Ejection Fraction

Novartis Pharmaceuticals465 participantsStarted Aug 2016

Birmingham, Alabama, United States • Little Rock, Arkansas, United States • Beverly Hills, California, United States +78 more locations

A Study of Oral LBH589 in Adult Patients With Advanced Hematological Malignancies

Study of Effects of Sacubitril/Valsartan vs. Enalapril on Aortic Stiffness in Patients With Mild to Moderate HF With Reduced Ejection Fraction

Find Trials by Condition in Houston

Study to Evaluate the Safety and Antiviral Activity of Remdesivir (GS-5734™) in Participants With Severe Coronavirus Disease (COVID-19)

Gliogene: Brain Tumor Linkage Study

Physical Activity After Endometrial Cancer

A Phase Ib/II Study of BYL719 and Cetuximab in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

Allogeneic Transplantation in Patients With Cutaneous T-Cell Lymphoma

The Effect of Sorafenib on Portal Pressure

Open-label Long Term (52 Weeks) Safety and Tolerability of Agomelatine Sublingual Tablets in Major Depressive Disorder (MDD)

A Dose Escalation Study in Solid Tumors and a Dose Expansion Study of PRN1371 in Adult Patients With Metastatic Urothelial Carcinoma

Efficacy, Safety and Tolerability of Agomelatine in the Treatment of Major Depressive Disorder

A Study of Palonosetron for the Prevention of Chemotherapy-Induced Nausea and Vomiting (CINV) in Participants Who Have Experienced CINV(Chemotherapy-Induced Nausea and Vomiting) During the Previous Cycle of Low Emetogenic Chemotherapy (LEC)

Topical CP-690,550 For Chronic Plaque Psoriasis

Study of Ibrutinib vs Placebo, in Combination With Nab-paclitaxel and Gemcitabine, in the First Line Treatment of Patients With Metastatic Pancreatic Adenocarcinoma (RESOLVE)

Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Alobresib (Formerly GS-5829) in Adults With Advanced Solid Tumors and Lymphomas and in Combination With Exemestane or Fulvestrant in Adults With Estrogen Receptor Positive Breast Cancer

DIAM™ Spinal Stabilization System vs. Decompression, Formerly vs. Posterolateral Fusion

A CLinical Study to Evaluate the Safety And Effectiveness of the CeRene DevIce to Treat HeavY Menstrual Bleeding

Study of Efficacy of PEAR-004 in Schizophrenia

Integrated Treatment for Youth With Mood Disorders

An Efficacy and Safety Study of Alirocumab in Children and Adolescents With Homozygous Familial Hypercholesterolemia