Clinical Trials in Houston

Showing 8141-8160 of 17,885 trials

Mesenchymal Stem Cells for Age-Related Frailty

NCT05284604

Frailty is a health state related to the aging process in which multiple body systems gradually lose their built-in reserves. It is a medical condition of reduced function in older adults which is associated with increased risks of adverse outcomes such as falls, disability, admission to hospital, or need for long-term care. Currently, there is no specific medical treatment of frailty. Mesenchymal stem cells (MSCs) are undifferentiated cells that self-replicated, and some may change into a particular cell type. These cells go to areas of injury due to signals released by injured cells. Upon reaching, the target tissue, MSCs repair injury by releasing growth factors and immune modulators to assist in the body's repair process. This initial study will assess the practicability of using MSCs for age-related frailty and provide information for planning a future full study of MSCs for maximizing Veteran's functional independence.

Frailty

VA Office of Research and DevelopmentStarted Jan 2023

Houston, Texas, United States

COMPLETEDPhase 2< 1 mile

Sargramostim Use in COVID-19 to Recover Patient Health

NCT04707664

The purpose of this research is to understand if the study drug, also called sargramostim or Leukine®, can help prevent the worsening of COVID-19 when the study drug is inhaled. This study will also help researchers understand if inhaled sargramostim can help prevent visits to the emergency room or hospitalization, or death.

Covid19SARS-CoV Infection

Partner Therapeutics, Inc.600 participantsStarted Apr 2021

Phoenix, Arizona, United States • Little Rock, Arkansas, United States • Canoga Park, California, United States +34 more locations

Mesenchymal Stem Cells for Age-Related Frailty

Sargramostim Use in COVID-19 to Recover Patient Health

Find Trials by Condition in Houston

Management of Chronic Pain and PTSD in Gulf War Veterans With tDCS+Prolonged Exposure

Study of the Safety and Efficacy of OPC-34712 as a Complementary Therapy in the Treatment of Adult Attention Deficit/Hyperactivity Disorder

PROTECTED TAVR: Stroke PROTECTion With SEntinel During Transcatheter Aortic Valve Replacement

Observational Study of Long Acting Injectable Medications (LAIs) in Schizophrenia (OASIS)

Atezolizumab and Bevacizumab Pre-Liver Transplantation for Patients With Hepatocellular Carcinoma Beyond Milan Criteria

Study to Evaluate the Efficacy and Safety of Intravenous Sulbactam-ETX2514 in the Treatment of Patients With Infections Caused by Acinetobacter Baumannii-calcoaceticus Complex

IO vs IV Vancomycin in Tourniquetless TKA

Assessing the Efficacy and Safety of Brolucizumab Versus Aflibercept in Patients With Visual Impairment Due to Macular Edema Secondary to Branch Retinal Vein Occlusion

ECG Belt for CRT Response

A Study to Assess the Safety and Tolerability of Different Doses of AG019 Administered Alone or in Combination With Teplizumab in Participants With Recent-onset Diagnosed Type 1 Diabetes (T1D)

SER-262 Versus Placebo in Adults With Primary Clostridium Difficile Infection to Prevent Recurrence

Inhaled ZYESAMI™ (Aviptadil Acetate) for the Treatment of Severe COVID-19

A Performance Evaluation Study of Arquer's MCM5 Elisa Test (ADXBLADDER) to Aid in the Monitoring of Recurrence in Non-Muscle Invasive Bladder Cancer

Study to Evaluate Safety and Pharmacokinetics of BIVIGAM® in Primary Immune Deficiency Subjects Aged 2 to 16

Location-based Smartphone Technology to Guide College Students Healthy Choices Ph II

ATHN 8: Previously Untreated Patients (PUPs) Matter Study

A Study of Fitusiran in Severe Hemophilia A and B Patients Previously Receiving Factor or Bypassing Agent Prophylaxis

Thoracolumbar Burst Fractures Study Comparing Surgical Versus Non-surgical Treatment