Clinical Trials in Houston

Showing 6801-6820 of 17,885 trials

InterLeukin-7 to Improve Clinical Outcomes in Lymphopenic Patients With COVID-19 Infection ( ILIAD-7-US-O )

NCT04426201

Comparison of the effects of CYT107 vs Placebo administered IM at 10μg/kg twice a week for three weeks on immune reconstitution of lymphopenic COVID-19 patients

COVID-19Lymphocytopenia

Revimmune10 participantsStarted Dec 2020

New York, New York, United States • Houston, Texas, United States

COMPLETEDPhase 1< 1 mile

A SAD/MAD to Assess the Safety, PK/PD of FT-4202 in Healthy Volunteers and Sickle Cell Disease Patients

NCT03815695

FT-4202 is an oral small-molecule agonist of pyruvate kinase red blood cell isozyme (PKR) being developed for the treatment of hemolytic anemias. This initial study will characterize the safety, tolerability and the pharmacokinetics/pharmacodynamics (PK/PD) of a single ascending dose and multiple ascending doses of FT-4202 in the context of Phase 1 studies in healthy volunteers and sickle cell disease patients. The effects of food on the absorption of FT-4202 will also be evaluated in healthy volunteers.

Healthy VolunteersSickle Cell Disease

Forma Therapeutics, Inc.130 participantsStarted Dec 2018

Little Rock, Arkansas, United States • Long Beach, California, United States • Oakland, California, United States +15 more locations

InterLeukin-7 to Improve Clinical Outcomes in Lymphopenic Patients With COVID-19 Infection ( ILIAD-7-US-O )

A SAD/MAD to Assess the Safety, PK/PD of FT-4202 in Healthy Volunteers and Sickle Cell Disease Patients

Find Trials by Condition in Houston

Allogeneic Heart Stem Cells to Achieve Myocardial Regeneration

Blinatumomab in Combination With AMG 404 for the Treatment of Adults With Relapsed or Refractory B Cell Precursor ALL

Study of Trofinetide for the Treatment of Girls and Women With Rett Syndrome (LAVENDER™)

H-22411: BOTOX® for Peyronie's Disease

A Study Evaluating the Safety, Pharmacokinetics, and Clinical Effects of Intravenously Administered PT-112 Injection in Subjects With Advanced Solid Tumors and Subsequent Dose Expansion Cohorts

Neoadjuvant and Adjuvant Checkpoint Blockade

TAC/MTX vs. TAC/MMF/PTCY for Prevention of Graft-versus-Host Disease and Microbiome and Immune Reconstitution Study (BMT CTN 1703/1801)

A Long-term Follow-up Study to Evaluate SKG0106 in the Treatment of Patients With nAMD

Safety and Feasibility of Umbilical Cord Wharton's Jelly Allograft Injections for Lumbar Pain

Safety and Effectiveness Study of the Zenflow Spring System

A Long-term Treatment With B-VEC for Dystrophic Epidermolysis Bullosa

Treatment Effects of Subcutaneous Injections of Pentosan Polysulfate Sodium vs Placebo in Participants With Knee OA Pain

Pilot Study to Examine the Feasibility of the Dynamic Interferential Spinal Cord Stimulation System™ (DISCSS™)

Palbociclib (PD-0332991) Combined With Fulvestrant In Hormone Receptor+ HER2-Negative Metastatic Breast Cancer After Endocrine Failure (PALOMA-3)

Study of Edecesertib in Participants With Cutaneous Lupus Erythematosus (CLE)

Evaluation of Product Performance of a New Silicone Hydrogel Multifocal Contact Lens

A Study of Avelumab in Combination With Axitinib In Non-Small Cell Lung Cancer (NSCLC) or Urothelial Cancer (Javelin Medley VEGF)

Study to Compare the Efficacy and Safety of Enzyme Replacement Therapies Avalglucosidase Alfa and Alglucosidase Alfa Administered Every Other Week in Patients With Late-onset Pompe Disease Who Have Not Been Previously Treated for Pompe Disease