Clinical Trials in Houston

Showing 5561-5580 of 17,885 trials

Evaluate the Safety, Tolerability, Pharmacodynamics and Efficacy of CNP-106 in Subjects With Myasthenia Gravis

NCT06106672

Phase 1b/2a First-in-Human (FIH) clinical trial to assess the safety, tolerability, pharmacodynamics (PD), and efficacy of multiple ascending doses of CNP-106.

Myasthenia GravisGeneralized MyastheniaAChR Myasthenia Gravis+1 more

COUR Pharmaceutical Development Company, Inc.54 participantsStarted May 2024

Phoenix, Arizona, United States • Phoenix, Arizona, United States • Brea, California, United States +14 more locations

TERMINATEDPhase 1/2< 1 mile

TK216 in Patients With Relapsed or Refractory Ewing Sarcoma

NCT02657005

Ewing sarcoma is characterized by genomic rearrangements resulting in over-expression of ets family transcription factors driving tumor progression. TK216 is designed to inhibit this effect by inhibiting downstream effects of the EWS-FLI1 transcription factor. This study is a first in human study of TK216 in subjects with Ewing sarcoma. The study is designed to establish initial safety and efficacy data in monotherapy and in combination with vincristine to assess the potential of TK216 for further development.

Sarcoma, Ewing

Oncternal Therapeutics, Inc85 participantsStarted Aug 2016

Los Angeles, California, United States • Aurora, Colorado, United States • Washington D.C., District of Columbia, United States +6 more locations

Evaluate the Safety, Tolerability, Pharmacodynamics and Efficacy of CNP-106 in Subjects With Myasthenia Gravis

TK216 in Patients With Relapsed or Refractory Ewing Sarcoma

Find Trials by Condition in Houston

ATHN 7: Hemophilia Natural History Study

LYT-200 Alone and in Combination With Chemotherapy or Tislelizumab in Patients With Locally Advanced or Metastatic Solid Tumors

Selumetinib and Cyclosporine in Treating Patients With Advanced Solid Tumors or Advanced or Metastatic Colorectal Cancer

A Study of ERAS-007 in Patients With Advanced Gastrointestinal Malignancies

A Study of Participants with Β-Thalassemia Treated with Betibeglogene Autotemcel

A Study of Imvotamab in Severe Systemic Lupus Erythematosus

(Concerto) Study of BLU-451 in Advanced Cancers With EGFR Exon 20 Insertion Mutations

A Pivotal Study of Safety and Effectiveness of NanoKnife IRE for Stage 3 Pancreatic Cancer

A Study of AK117 in Combination With Azacitidine in Patients With Myelodysplastic Syndromes

A Trial of a Novel XPO1 Inhibitor in Participants With Advanced Solid Tumors

A Study to Evaluate the Pharmacokinetics, Safety and Tolerability of Upadacitinib in Pediatric Participants With Severe Atopic Dermatitis

Artoss Prospective Spine Registry Outcomes

A Study of SGN-ALPV in Advanced Solid Tumors

Surveillance and Alert-based Multiparameter Monitoring to Reduce Worsening Heart Failure Events

At-Risk for Type 1 Diabetes Extension Study (TN-10 Extension)

A Clinical Trial to Evaluate the Safety, Tolerability, and Pharmacokinetics of PGDM1400LS Alone and in Combination With VRC07-523LS and PGT121.414.LS in Healthy, HIV-uninfected Adult Participants

Non-comparative Study of IFX-1 Alone or IFX-1+Pembrolizumab in Patients With Locally Advanced or Metastatic cSCC.

Rising Tide - Amniotic Tissue(s) Treatments for Chronic Diabetic Foot Ulcers