Clinical Trials in Houston

Showing 4821-4840 of 17,885 trials

Study of AZD0466 Monotherapy or in Combination in Patients With Advanced Haematological Malignancies

NCT04865419

The purpose of the study is to the evaluate safety, tolerability, pharmacokinetics (PK), and efficacy of AZD0466 as monotherapy in partciapants with advanced haematological malignancies and also to assess drug-drug interaction (DDI) potential between AZD0466 and the azole antifungal voriconazole.

Haematological Malignancies

AstraZeneca46 participantsStarted Jun 2021

Duarte, California, United States • Jacksonville, Florida, United States • Chicago, Illinois, United States +12 more locations

Enrolling By Invitation< 1 mile

REpeated ASSEssment of SurvivorS in Intracerebral Hemorrhage Study

NCT05611918

The investigators propose to perform serial detailed cognitive, motor, behavioral, and blood collection follow-up using longitudinal structured telephone interviews of an anticipated 350 ICH survivors enrolled in Minimally Invasive Surgery Plus Alteplase for Intracerebral Hemorrhage Evacuation (MISTIE) III and ENRICH trials to identify specific cognitive and motor impairment and to perform RNA sequencing to evaluate for evidence of chronic inflammation. The investigators' expected sample size in 2022 accounts for mortality attrition of 10%/year.

Intra Cerebral HemorrhageICH - Intracerebral HemorrhageICH+9 more

Johns Hopkins University350 participantsStarted May 2023

Birmingham, Alabama, United States • La Jolla, California, United States • Sacramento, California, United States +23 more locations

Study of AZD0466 Monotherapy or in Combination in Patients With Advanced Haematological Malignancies

REpeated ASSEssment of SurvivorS in Intracerebral Hemorrhage Study

Find Trials by Condition in Houston

DETECT-RPC Universal EM Screening

A Prospective Study of a Modified Lumbar Puncture (LP) Procedure That Reduces Post-Lumbar Puncture Headaches (PLPH) in Patients

A Study of Unesbulin in Participants With Advanced Leiomyosarcoma (LMS)

Shared-Decision Making for Hydroxyurea

Diagnostic Performance Study of the EMVision Emu™ Brain Scanner in the Detection of Intracranial Hemorrhage in Suspected Stroke Patients

Testing the Effects of MK-3475 (Pembrolizumab) With or Without the Usual Chemotherapy Treatment for Patients 70 Years of Age and Older With Advanced Non-small Cell Lung Cancer

Enfortumab Vedotin and Pembrolizumab vs. Chemotherapy Alone in Untreated Locally Advanced or Metastatic Urothelial Cancer

Investigating Geographic Atrophy Insights (i-GAIN) Natural History Study

Effect of Hepatic Impairment on the Pharmacokinetics and Safety of VIR-2218 and VIR-3434

Reproductive Health Program in Patients With Cancer

A Study to Determine the Efficacy and Safety of Deucravacitinib Compared With Placebo in Participants With Active Psoriatic Arthritis (PsA) Who Are Naïve to Biologic Disease Modifying Anti-rheumatic Drugs or Had Previously Received TNFα Inhibitor Treatment

PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm

A Follow-On Study of Donanemab (LY3002813) With Video Assessments in Participants With Alzheimer's Disease (TRAILBLAZER-EXT)

The Role of Electrophysiology Testing in Survivors of Unexplained Cardiac Arrest

Cangrelor in Acute Myocardial Infarction: Effectiveness and Outcomes Registry

Open-Label Study of the CDK4/6 Inhibitor SPH4336 in Subjects With Locally Advanced or Metastatic Liposarcomas

ColoCare Study - Colorectal Cancer Cohort

A Study of TAK-079 in Adults With Persistent/Chronic Primary Immune Thrombocytopenia