Clinical Trials in Houston

Showing 2301-2320 of 15,366 trials

Study of Pembrolizumab (MK-3475) in Combination With Romidepsin

NCT03278782

This phase I/II trial studies the side effects of pembrolizumab and romidepsin and to see how well they work in treating participants with peripheral T-cell lymphoma that has come back or that does not respond to treatment. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Romidepsin may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Giving pembrolizumab and romidepsin may work better than pembrolizumab alone in treating participants with recurrent or refractory peripheral T-cell lymphoma.

Recurrent Anaplastic Large Cell LymphomaRecurrent Angioimmunoblastic T-Cell LymphomaRecurrent Mature T- and NK-Cell Non-Hodgkin Lymphoma+8 more

M.D. Anderson Cancer Center39 participantsStarted Nov 2017

Houston, Texas, United States

Active Not RecruitingNA< 1 mile

Safety and Efficacy of Polymyxin B Hemoperfusion (PMX) for Endotoxemic Septic Shock in a Randomized, Open-Label Study

NCT03901807

Prospective, multicenter, randomized, open-label study of standard of care plus the PMX cartridge versus standard of care alone in patients with endotoxemic septic shock

Septic ShockEndotoxemia

Spectral Diagnostics (US) Inc.150 participantsStarted Jan 2020

Birmingham, Alabama, United States • Little Rock, Arkansas, United States • San Francisco, California, United States +17 more locations

Study of Pembrolizumab (MK-3475) in Combination With Romidepsin

Safety and Efficacy of Polymyxin B Hemoperfusion (PMX) for Endotoxemic Septic Shock in a Randomized, Open-Label Study

Find Trials by Condition in Houston

Phase III Study of Rilvegostomig in Combination With Bevacizumab With or Without Tremelimumab as First-line Treatment of Hepatocellular Carcinoma

Efficacy of Placental Membrane Dressings in Accelerating Diabetic Foot Healing

Shoulder iD™ Primary Reversed Glenoid Outcomes Clinical Study

A Study Assessing Adverse Event and How Oral ABBV-453 Moves Through the Body in Adult Participants With Relapsed or Refractory (R/R) Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)

Combo of Cabozantinib With Abiraterone in Chemotherapy-Naïve Subjects With Bone-Metastatic CRPC

RESTORE: REducing Future fractureS and Improving ouTcOmes of fRagility fracturE

A Study to Assess Adjuvant Immunotherapy With Nivolumab Plus Relatlimab Versus Nivolumab Alone After Complete Resection of Stage III-IV Melanoma

tAN for Substance Use Disorder

A Dose Escalation Study of AV-380 in Cancer Patients With Cachexia

Study of Bitopertin to Evaluate the Safety, Tolerability, Efficacy, and PPIX Concentrations in Participants With EPP

A Phase 1/2 Study to Investigate CRB-701 in Solid Tumors

A Phase 3, Randomized, Double Blind, Placebo-Controlled, Multi-Center, Withdrawal Study of MCI-196 in CKD on Dialysis With Hyperphosphatemia

A Phase 1b/2 Study of ADG116, ADG116 Combined With Anti-PD-1 Antibody or Anti-CD137 Antibody in Solid Tumors Patients

Investigation of the Two Level Simplify® Cervical Artificial Disc

Post Approval Study Protocol for the Two Level Simplify® Cervical Artificial Disc

Evaluation of COVID-19 and Flu A/B 3 in 1 Combo Rapid Test

A Study to Evaluate the Efficacy and Safety of Golcadomide in Combination With Rituximab in Participants With Newly Diagnosed Advanced Stage Follicular Lymphoma

A Study of Relatlimab in Combination With Nivolumab in Participants With Advanced Liver Cancer Who Have Never Been Treated With Immuno-oncology Therapy After Prior Treatment With Tyrosine Kinase Inhibitors