Clinical Trials in Georgia

Showing 1281-1300 of 16,324 trials

A Study Evaluating the Effectiveness and Safety of Risdiplam Administered as an Early Intervention in Pediatric Participants With Spinal Muscular Atrophy After Gene Therapy

NCT05861986

This is an open-label, single-arm, multicenter clinical study to evaluate the effectiveness and safety of risdiplam administered as an early intervention in pediatric participants with spinal muscular atrophy (SMA) and 2 SMN2 copies who have previously received onasemnogene abeparvovec. Participants are children \< 2 years of age genetically diagnosed with SMA.

Muscular Atrophy, Spinal

Hoffmann-La Roche28 participantsStarted May 2024

Little Rock, Arkansas, United States • Aurora, Colorado, United States • Gainesville, Florida, United States +13 more locations

RECRUITINGPhase 165 miles

Study of AMG 509 in Participants With Metastatic Castration-Resistant Prostate Cancer

NCT04221542

The overall aim of the trial is to evaluate the safety, tolerability, and pharmacokinetics (PK) of AMG 509 (monotherapy and in combination with abiraterone acetate and enzalutamide) and to evaluate preliminary efficacy. As of Protocol Amendment 10 (09 July 2025), only Parts 4A expansion, 6, and 7 are open to accrual.

Prostate Cancer

Amgen479 participantsStarted Mar 2020

Duarte, California, United States • Fullerton, California, United States • San Francisco, California, United States +53 more locations

A Study Evaluating the Effectiveness and Safety of Risdiplam Administered as an Early Intervention in Pediatric Participants With Spinal Muscular Atrophy After Gene Therapy

Study of AMG 509 in Participants With Metastatic Castration-Resistant Prostate Cancer

Find Trials by Condition in Georgia

REVEAL Biomarkers of Engraftment After Alternative Donor HSCT

A Study to Assess the Long-term Safety and Efficacy of ATB200/AT2221 in Adult Subjects With Late-Onset Pompe Disease (LOPD)

Impella ECP Study (ECP Study) and Impella ECP Continued Access Protocol

Higher Per Daily Treatment-Dose Radiation Therapy or Standard Per Daily Treatment Radiation Therapy in Treating Patients With Early-Stage Breast Cancer That Was Removed by Surgery

CDC-9 Inactivated Rotavirus Vaccine (IRV) Microneedle Patch (MNP) in Healthy Adults

Effect of Retatrutide Compared With Placebo in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Diet and Exercise Alone (TRANSCEND-T2D-1)

Interstitial Brachytherapy With or Without External-Beam Radiation Therapy in Treating Patients With Prostate Cancer

Collection and Storage of Tissue and Blood Samples From Patients With Cancer

Study of Trastuzumab Deruxtecan With Bevacizumab Versus Bevacizumab Monotherapy for First-line Maintenance in HER2-Expressing Ovarian Cancer (DESTINY-Ovarian01)

Implementation of Whole Genome Sequencing as Screening in a Diverse Cohort of Healthy Infants

DISCOVERY of Risk Factors for Type 2 Diabetes in Youth

Ibrutinib and Ixazomib Citrate in Treating Newly Diagnosed, Relapsed or Refractory Waldenstrom Macroglobulinemia

Trifecta-Lung cfDNA-MMDx Study

Master Protocol for Evaluating Multiple Infection Diagnostics for Ciprofloxacin-Resistant Neisseria Gonorrhoeae

Post-sleeve Gastrectomy Gastroesophageal Reflux Disease Prediction

Safety and Efficacy of MK-1200 in Participants With Advanced Solid Tumors (MK-1200-002)

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of NXT007 in Persons With Severe or Moderate Hemophilia A

Systemic and Topical Antivirals for Control of Cytomegalovirus Anterior Uveitis: Treatment Outcomes