Clinical Trials in Georgia

Showing 5581-5600 of 19,050 trials

A Study Evaluating the Safety and Efficacy of Lovo-cel in Severe Sickle Cell Disease

NCT02140554

This is a non-randomized, open label, multi-site, single dose, Phase 1/2 study in approximately 50 adults and adolescents with severe SCD. The study will evaluate hematopoietic stem cell and progenitor stem cell (collectively referred to as hematopoietic stem and progenitor cells or HSPCs) transplantation using lovo-cel.

Sickle Cell Disease

Genetix Biotherapeutics Inc.54 participantsStarted Feb 2015

Birmingham, Alabama, United States • Oakland, California, United States • Atlanta, Georgia, United States +8 more locations

COMPLETEDPhase 2/365 miles

Study Understanding Pre-Exposure pRophylaxis of NOVel Antibodies (SUPERNOVA) Sub-study: Study Understanding Pre-Exposure pRophylaxis of NOVel Antibodies (SUPERNOVA) Sub-study

NCT05648110

AZD3152, a single mAb, is being developed to have broad neutralizing activity across known SARS-CoV-2 variants of concern for pre-exposure prophylaxis of COVID-19. The aim of the Phase I/III study (Parent Study) will be to evaluate the safety, efficacy and neutralizing activity of AZD3152 compared with comparator for pre exposure prophylaxis of COVID-19, and separately evaluate the safety and PK of AZD5156, a combination of AZD3152 and AZD1061. Sub-study: This Phase II sub-study of SUPERNOVA will assess the safety, PK, and predicted neutralizing activity of AZD3152 compared with EVUSHELD for pre-exposure prophylaxis of COVID-19.

COVID-19, SARS-CoV-2

AstraZeneca3,882 participantsStarted Dec 2022

Birmingham, Alabama, United States • Birmingham, Alabama, United States • Mobile, Alabama, United States +212 more locations

A Study Evaluating the Safety and Efficacy of Lovo-cel in Severe Sickle Cell Disease

Study Understanding Pre-Exposure pRophylaxis of NOVel Antibodies (SUPERNOVA) Sub-study: Study Understanding Pre-Exposure pRophylaxis of NOVel Antibodies (SUPERNOVA) Sub-study

Find Trials by Condition in Georgia

WAveCrest Vs. Watchman TranssEptal LAA Closure to REduce AF-Mediated STroke 2

Clinical Trial to Evaluate Safety and Efficacy of CCX168 in ANCA-Associated Vasculitis

A Study to Evaluate the Safety of mRNA-0184 in Participants With Heart Failure

A Study of the Effect of Testosterone Replacement Therapy on Blood Pressure in Adult Male Participants With Hypogonadism

Trial to Shorten Pharmacologic Treatment of Newborns With Neonatal Opioid Withdrawal Syndrome (NOWS)

An Evaluation of LEO 138559 in Adults With Moderate to Severe Atopic Dermatitis.

A Study of INCB050465 in Relapsed or Refractory Follicular Lymphoma

A Phase 1/2 Trial of CLN-081 in Patients With Non-Small Cell Lung Cancer

p53 Suppressor Activation in Recurrent High Grade Serous Ovarian Cancer, a Phase Ib/II Study of Systemic Carboplatin Combination Chemotherapy With or Without APR-246

SNV1521 in Participants with Advanced Solid Tumors

A Study Comparing Two Formulations of Selpercatinib (LY3527723) in Healthy Participants

A Phase 1/2 Study of VIO-01 in Participants With Recurrent Solid Tumors

A Study of LY3561774 in Participants With Mixed Dyslipidemia

Volatile Anaesthesia and Perioperative Outcomes Related to Cancer: the VAPOR-C Trial

Angio-IMR and Cardiac MR-derived MVO in STEMI Patients

Vestibular Stimulation to Trigger Adipose Loss (VeSTAL) Clinical Trial

Pivotal, Clinical Study for the Accuracy Evaluation of the IdentiClone Dx TRG Assay

Infant Mortality Reduction by the Mass Administration of Azithromycin