Clinical Trials in Georgia

Showing 5421-5440 of 19,050 trials

MRI to Characterize and Predict CF Liver Disease in PUSH Cohort

NCT02979340

Specific Aim 1. Determine if valid results of non-sedated MRI based assessments of liver stiffness and lipid content can be obtained in more than 90% of children and young adults with cystic fibrosis. Specific Aim 2. Determine hepatic lipid content using the HepaFat sequence and liver stiffness using MRE. Investigators will compare the results obtained by MRI with PUSH study grayscale ultrasounds in CF patients with normal, heterogeneous, homogeneous or nodular (cirrhotic) pattern on ultrasound. Specific Aim 3. Creation of an imaging core lab to centralize evaluation of MR imaging data, allow for remote image upload, electronic data storage, and remote image viewing/interpretation. This infrastructure will be utilized to standardize image post processing. Specific Aim 4. Using the longitudinal PUSH study, determine if MRI based imaging improves discrimination of subjects at risk for progression to advanced CF liver disease (development of cirrhosis) compared to using US imaging alone

Cystic Fibrosis Liver DiseasePancreatic Insufficiency

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)115 participantsStarted Jan 2017

Aurora, Colorado, United States • Atlanta, Georgia, United States • Indianapolis, Indiana, United States +5 more locations

COMPLETEDPhase 165 miles

A Study of BMS-986416 With and Without Nivolumab in Select Solid Tumors

NCT04943900

The purpose of this study is to evaluate the safety, tolerability, drug effects, drug levels and preliminary antitumor activity of BMS-986416 when administered alone and in combination with Nivolumab in participants with select advanced solid tumors.

Advanced Solid Tumors

Bristol-Myers Squibb67 participantsStarted Aug 2021

Atlanta, Georgia, United States • Baltimore, Maryland, United States • Hackensack, New Jersey, United States +16 more locations

MRI to Characterize and Predict CF Liver Disease in PUSH Cohort

A Study of BMS-986416 With and Without Nivolumab in Select Solid Tumors

Find Trials by Condition in Georgia

AtRial Cardiopathy and Antithrombotic Drugs In Prevention After Cryptogenic Stroke

FEED-Cystic Fibrosis (FEED-CF)

A Phase 3 Study of Efficacy and Safety of Remibrutinib in the Treatment of CSU in Adults Inadequately Controlled by H1 Antihistamines

Rituximab, Bendamustine Hydrochloride, and Bortezomib Followed by Rituximab and Lenalidomide in Treating Older Patients With Previously Untreated Mantle Cell Lymphoma

A Randomized, Controlled Trial to Evaluate the Safety and Effectiveness of the Route 92 Medical Reperfusion System (SUMMIT MAX)

Long-term Follow-up of Subjects With Transfusion-Dependent β-Thalassemia (TDT) Treated With Ex Vivo Gene Therapy

Study of the Adverse Events and Change in Disease State of Pediatric Participants (and Young Adults Between the Ages of 18-25) With Relapsed/Refractory Aggressive Mature B-cell Neoplasms Receiving Subcutaneous (SC) Injections of Epcoritamab

REGN2810 in Pediatric Patients With Relapsed, Refractory Solid, or Central Nervous System (CNS) Tumors and Safety and Efficacy of REGN2810 in Combination With Radiotherapy in Pediatric Patients With Newly Diagnosed or Recurrent Glioma

Performance and Safety of a Digital Tool for Unsupervised Self-assessment of NMOSD

Ziprasidone in Bipolar Disorder With Comorbid Lifetime Panic or Generalized Anxiety Disorder(GAD)

Amivantamab in Adenoid Cystic Carcinoma

Study of Efficacy of CML-CP Patients Treated With ABL001 Versus Bosutinib, Previously Treated With 2 or More TKIs

Tezepelumab Efficacy and Safety in Reducing Oral Corticosteroid Use in Adults With Oral Corticosteroid Dependent Asthma

A Study of ADRX-0405 in Subjects With Select Advanced Solid Tumors

Study of ASTX295 in Patients With Solid Tumors With Wild-Type p53

Safety Study of XT-150 in Participants With ALS

Study to Evaluate the Efficacy of a Probiotic in Infantile Colic Symptoms Relief

Trial of the Impact of Sibeprenlimab on Immunoglobulin A Nephropathy Kidney Tissue