Clinical Trials in Detroit

Showing 18641-18660 of 19,719 trials

A Study of the Efficacy and Safety of ICA-17043 (With or Without Hydroxyurea) in Patients With Sickle Cell Anemia.

NCT00040677

ICA-17043 is being developed for the chronic treatment of patients with sickle cell disease (SCD) in both adults and children. ICA-17043 is a potent and specific inhibitor of a channel in human red blood cells (RBCs) that blocks RBC dehydration. ICA-17043 is expected to inhibit RBC dehydration and thus should prevent or delay the sickling process. By reducing sickled cells, an improvement in anemia, a reduction in painful crises, and ultimately, less end-organ disease is anticipated.

Sickle Cell DiseaseSickle Cell Anemia

Icagen90 participantsStarted Feb 2002

Birmingham, Alabama, United States • Oakland, California, United States • San Francisco, California, United States +16 more locations

No Longer Available2.6 miles

Oral Nilotinib in Adults With Chronic Myeloid Leukemia (CML) in Blast Crisis Who Are Imatinib Resistant or Intolerant

NCT00413270

This study will evaluate the safety of nilotinib in adult patients with imatinib-resistant or -intolerant CML-blast crisis, CML-accelerated phase or CML-chronic phase when treated with nilotinib. Patients will be provided access to nilotinib until the drug is available on the market.

Chronic Myelogenous Leukemia

Novartis PharmaceuticalsStarted Dec 2006

Calgary, Alberta, Canada • Edmonton, Alberta, Canada • Burnaby, British Columbia, Canada +15 more locations

A Study of the Efficacy and Safety of ICA-17043 (With or Without Hydroxyurea) in Patients With Sickle Cell Anemia.

Oral Nilotinib in Adults With Chronic Myeloid Leukemia (CML) in Blast Crisis Who Are Imatinib Resistant or Intolerant

Find Trials by Condition in Detroit

Study of the Glycemic Effects of Nebivolol Compared With Metoprolol and HCTZ in Diabetic Hypertensive Patients

Randomized Trial Of Tinnitus Retraining Therapy

TLK286 (Telcyta) vs. Doxil/Caelyx or Hycamtin in Platinum Refractory or Resistant Ovarian Cancer

Injection of Autologous CD34-Positive Cells for Critical Limb Ischemia

A Phase 1-2, Multicenter, Open-Label Study of AEG35156 in Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia and Indolent B-Cell Lymphomas

A Study for Adults With Plaque Psoriasis

A Study for Patients With Type 2 Diabetes Mellitus

Oral Vitamin K for Warfarin Associated Coagulopathy

A Comparison of Zidovudine (AZT) and Stavudine in HIV-Infected Patients

Open Label Study Of SU011248 In Combination With Trastuzumab For Patients With Metastatic Breast Cancer

TBTC NAA Study: Pilot Study of Surrogate Markers for Outcome of TB Treatment

An Open-Label Comparison of Duloxetine to Other Alternatives for the Management of Diabetic Peripheral Neuropathic Pain

Chemoprevention Therapy in Treating Patients at High Risk of Developing Multiple Myeloma

A Clinical Study to Assess the Safety of a New Influenza Vaccine

A Study to Evaluate the Neovista Ophthalmic System for the Treatment of Subfoveal CNV in Patients With AMD That Have Failed Primary Anti-VEGF Therapy

Insertion of an Intrauterine Device (IUD) After Medical Abortion

A Prospective Study to Evaluate the Safety of a New Monovalent Intranasal Influenza Vaccine

A Phase 4 Two Dose Level Study of Naglazyme(TM) (Galsulfase) in Infants With MPS VI