Clinical Trials in Detroit

Showing 18061-18080 of 19,719 trials

A Pilot Study of Biomarkers for Spinal Muscular Atrophy

NCT00756821

The goal of this pilot study is to identify a marker or panel of markers in the blood or urine from a wide range of Spinal Muscular Atrophy (SMA) patients that segregates with measures of clinical severity. From this identification of candidate biomarkers, it is hoped that further investigations, both longitudinal natural history and clinical efficacy studies, will verify a biomarker with the sensitivity and specificity that will allow its eventual use as a validated pharmacodynamic marker or surrogate endpoint. In addition, this effort may elucidate biological pathways that may be potential therapeutic targets.

Spinal Muscular Atrophy

Carelon Research130 participantsStarted Oct 2008

Birmingham, Alabama, United States • Stanford, California, United States • Aurora, Colorado, United States +15 more locations

COMPLETED2.6 miles

Canadian Study of Trandolapril on Blood Pressure in Hypertensive Patients

NCT01078584

The in-MAU-tion study is conducted to determine the percentage of hypertensive participants with or without diabetes reaching CHEP (Canadian Hypertension Education Program) defined blood pressure targets. Additionally, the study assesses change in renal function (microalbuminuria, estimated glomerular filtration rate) in hypertensive participants treated with trandolapril (Mavik®) and examines patient satisfaction with trandolapril (Mavik®) therapy.

Hypertension

Abbott7,993 participantsStarted Dec 2008

Calgary, Alberta, Canada • Calgary, Alberta, Canada • Calgary, Alberta, Canada +565 more locations

A Pilot Study of Biomarkers for Spinal Muscular Atrophy

Canadian Study of Trandolapril on Blood Pressure in Hypertensive Patients

Find Trials by Condition in Detroit

Follow-Up Study for Exubera

Correlating Outcomes With Biochemical Markers to Estimate Time-progression in Idiopathic Pulmonary Fibrosis (IPF)

Effect of Rosiglitazone on Peritoneal Cytokines in Women With Endometriosis

Safety, Tolerability and Efficacy Study to Evaluate Subjects With Mild Cognitive Impairment

Study to Evaluate Safety, Tolerability, and Effect of AL208 on Mild Cognitive Impairment Following Coronary Artery Bypass Graft Surgery

Study Evaluating the Pharmacokinetics (PK), Safety, and Tolerability of Tigecycline in Patients 8 to 11 Years of Age

Long-Term Assessment for Metabolic, Cardiovascular and Neurologic Problems in HIV-Infected Patients With Increased CD4 Cells Counts Following Anti-HIV Therapy

Prevalence of Chronic Airway Obstruction in Subjects With a History of Cigarette Smoking in a Primary Care Setting

Effects of Chitin-Glucan on Oxidized Low-Density Lipoprotein (LDL)

Megadyne Ace Incision/Dissection Study

Dyslipidemia Study Investigating The Increase In "Good Cholesterol"

Open-Label Study to Evaluate the Effect of Treatment With Fentanyl Buccal Tablets on Pain Anxiety Symptoms When Used for the Management of Breakthrough Pain

Belatacept in Liver Transplant Recipients

Evaluation of the Cardioblate Closure Device in Facilitating Occlusion of the Left Atrial Appendage

Docetaxel and Imatinib Mesylate in Treating Patients With Androgen-Independent Prostate Cancer and Bone Metastases That Progressed on the Docetaxel and Placebo Group of MDA-ID-030008

Vaccine Response After Rituximab for Chronic, Severe Idiopathic Thrombocytopenic Purpura

A Study for the Transdermal Application of Teriparatide

Drug Interactions Between Voriconazole and Atazanavir Coadministered as Atazanavir/Ritonavir in Healthy Participants