Clinical Trials in Detroit

Showing 17721-17740 of 19,719 trials

Gefitinib and Celecoxib in Treating Patients With Refractory Non-Small Cell Lung Cancer

NCT00068653

RATIONALE: Gefitinib may stop the growth of tumor cells by blocking the enzymes necessary for tumor cell growth. Celecoxib may slow the growth of cancer by stopping blood flow to the tumor. Combining gefitinib with celecoxib may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of combining gefitinib with celecoxib in treating patients who have non-small cell lung cancer that is refractory to platinum-based chemotherapy (such as cisplatin or carboplatin).

Lung Cancer

Barbara Ann Karmanos Cancer Institute27 participantsStarted Jun 2003

Detroit, Michigan, United States

TERMINATEDPhase 36.7 miles

Combination Chemotherapy Before or After Surgery in Treating Patients With Colorectal Cancer With Liver Metastases That Could Be Removed By Surgery

NCT01189227

RATIONALE: Drugs used in chemotherapy work in different ways to kill tumor cells or stop them from growing. Giving combination chemotherapy before surgery may make the tumor smaller and reduce the amount of normal tissue that needs to be removed. Giving combination chemotherapy after surgery may kill any remaining tumor cells. It is not yet known whether giving combination chemotherapy before and after surgery is more effective than giving combination chemotherapy after surgery. PURPOSE: This randomized phase III trial is studying giving combination chemotherapy before and after surgery to see how well it works compared to giving combination chemotherapy after surgery in treating patients with colorectal cancer with liver metastases that could be removed by surgery.

Colorectal CancerMetastatic Cancer

NSABP Foundation Inc9 participantsStarted Aug 2010

Antioch, California, United States • Duarte, California, United States • Fremont, California, United States +280 more locations

Gefitinib and Celecoxib in Treating Patients With Refractory Non-Small Cell Lung Cancer

Combination Chemotherapy Before or After Surgery in Treating Patients With Colorectal Cancer With Liver Metastases That Could Be Removed By Surgery

Find Trials by Condition in Detroit

Efficacy and Safety Study of Uracyst to Treat Interstitial Cystitis/Painful Bladder Syndrome

A Phase 2 Dose Ranging, Evaluator-Blinded Study to Evaluate the Safety of Topical IDP-118

Vorinostat and Temozolomide in Treating Young Patients With Relapsed or Refractory Primary Brain Tumors or Spinal Cord Tumors

A Pharmacokinetics, Pharmacodynamics and Safety Study of Rabeprazole in New Born Infants With Gastroesophageal Reflux Disease (GERD)

Famciclovir Pediatric Formulation in Children 1 to 12 Years of Age With Herpes Simplex Infection

Safety/Efficacy of Everolimus in Adults With Advanced Pancreatic Neuroendocrine Cancer Not Responsive to Chemotherapy

Drug Eluting Stent Registry of Thrombosis

A Study of a 35 mg Delayed Release Formulation of Risedronate for Osteoporosis

Study of Safety and Efficacy of PF-04991532 in Subjects With Type 2 Diabetes

Doxycycline and OA Progression

Advisa MRI Clinical Study

Cognitive REmediation After Trauma Exposure Trial = CREATE Trial

Pancreatic Cancer Serum and DNA Repository

Phase II Study of Dasatinib (BMS-354825) for Androgen-deprived Progressive Prostate Cancer

The PediQUEST Study: Evaluation of Pediatric Quality of Life and Evaluation of Symptoms Technology

Dose Escalation Study of ARQ 736 in Adult Subjects With Advanced Solid Tumors Harboring BRAF and/or NRAS Mutations

Phased Treatment for Social Anxiety Disorder and Coping Behaviors in a Medical Setting

Study of Parathyroid Hormone Following Sequential Cord Blood Transplantation From an Unrelated Donor