Clinical Trials in Detroit

Showing 16921-16940 of 19,719 trials

Minimally-Invasive Cardiovascular Hemodynamic Optimization (MiCHO) Versus Early Goal-Directed Therapy (EGDT) in the Management of Septic Shock

NCT00535821

Early intervention in the treatment of septic shock, including early goal-directed therapy (EGDT) in the first 6 hours of disease presentation, has been shown to significantly decrease mortality. However, this approach requires invasive hemodynamic monitoring, thus limiting its widespread application in the emergency department setting. A minimally invasive protocol utilizing esophageal Doppler monitoring (EDM) may be of benefit and practical if it is shown to result in similar outcome as EGDT.

Severe SepsisSeptic Shock

Loma Linda University5 participantsStarted Jun 2007

Loma Linda, California, United States • Loma Linda, California, United States • Worcester, Massachusetts, United States +1 more locations

COMPLETEDNA< 1 mile

A Nutritional Supplement Capsule Containing Curcumin, Green Tea Extract, Polygonum Cuspidatum Extract, and Soybean Extract in Healthy Participants

NCT00768118

RATIONALE: Studying samples of blood and urine from healthy participants receiving antioxidant nutritional supplements may help doctors identify changes in biomarkers related to oxidative stress. PURPOSE: This clinical trial is studying how well a nutritional supplement capsule containing curcumin, green tea extract, Polygonum cuspidatum extract, and soybean extract works in healthy participants.

Healthy, no Evidence of Disease

Barbara Ann Karmanos Cancer Institute11 participantsStarted Apr 2008

Detroit, Michigan, United States

COMPLETEDPhase 316 miles

Study to Evaluate the Safety and Efficacy of Androxal Treatment in Men With Secondary Hypogonadism

NCT01067365

Subjects who completed ZA-003 were eligible to receive an additional year of treatment in this extension study.

Secondary Hypogonadism

Repros Therapeutics Inc.104 participantsStarted Mar 2006

Birmingham, Alabama, United States • Huntsville, Alabama, United States • Carmichael, California, United States +15 more locations

Minimally-Invasive Cardiovascular Hemodynamic Optimization (MiCHO) Versus Early Goal-Directed Therapy (EGDT) in the Management of Septic Shock

A Nutritional Supplement Capsule Containing Curcumin, Green Tea Extract, Polygonum Cuspidatum Extract, and Soybean Extract in Healthy Participants

Study to Evaluate the Safety and Efficacy of Androxal Treatment in Men With Secondary Hypogonadism

Find Trials by Condition in Detroit

Safety and Tolerability of Dalfampridine in Subjects With Cerebral Palsy

Dose Range Finding Study of Fedovapagon in Men With Nocturia

The Effect of Platform Switching on Single Implants in the Esthetic Zone, Following Flapless Surgery and Early-Loading Protocols

An Efficacy and Safety Study for Yondelis (Trabectedin) in Patients With Advanced Relapsed Ovarian Cancer

Safety and Efficacy of BI 1744 CL in Patients With Chronic Obstructive Pulmonary Disease I

A Multicenter Study of rhFGF 18 in Patients With Knee Osteoarthritis Not Requiring Surgery

Open-Label, Multicenter Extension Study for Patients Completing Treatment Phase of a Rigel-Sponsored R935788 Studies

Safety and Efficacy of Once-Daily KRP-104 in Type 2 Diabetics With Inadequate Glycemic Control on Metformin Alone

Safety and Immunogenicity of MF59C.1 Adjuvanted Trivalent Subunit Influenza Vaccine in Elderly Subjects

Non-traditional Cardiovascular Risk Factors and Atherosclerosis in Type 2 Diabetes

Citalopram for Agitation in Alzheimer's Disease

A Multi-center Long Term Efficacy Trial of the GFX For Reduction of Glabellar Furrowing

A Study to Evaluate the Efficacy and Safety of Flexible Doses of Extended-release (ER) Paliperidone Compared With Flexible Doses of Quetiapine and Placebo in Patients With Bipolar I Disorder

A Study of TMC278 in Human Immunodeficiency Virus Type 1 Infected Patients, Who Are Not Treated With Antiretroviral Medicines

Evaluation of the Safety, Tolerability, Pharmacokinetics, and Activity of GS-9450 in Subjects With Chronic HCV

Comparison of Ipilimumab Manufactured by 2 Different Processes in Participants With Advanced Melanoma

Clinical Evaluation of the Physiological Diagnosis Function in the PARADYM CRT Device