Clinical Trials in Detroit

Showing 14681-14700 of 19,719 trials

Study Evaluating Inotuzumab Ozogamicin In Acute Lymphocytic Leukemia

NCT01363297

The Phase 1 portion of this study will assess the safety, tolerability and efficacy at increasing dose levels of inotuzumab ozogamicin in subjects with CD22-positive relapsed or refractory adult acute lymphocytic leukemia (ALL) in order to select the recommended phase 2 dose (RP2D) and schedule. The Phase 2 portion of the study will evaluate the efficacy of inotuzumab ozogamicin as measured by hematologic remission rate (CR + CRi) in patients in second or later salvage status.

Acute Lymphocytic Leukemia

Pfizer72 participantsStarted Aug 2011

Duarte, California, United States • Palo Alto, California, United States • Palo Alto, California, United States +12 more locations

COMPLETEDPhase 1< 1 mile

A Study Evaluating the Safety, Tolerability, and Pharmacokinetics of GDC-0425 Administered With and Without Gemcitabine in Patients With Refractory Solid Tumors or Lymphoma

NCT01359696

This is an open-label, multicenter, Phase I, dose-escalation study to assess the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of GDC-0425 administered with and without gemcitabine.

Solid Tumor

Genentech, Inc.40 participantsStarted Jul 2011

Detroit, Michigan, United States • Nashville, Tennessee, United States • Villejuif, France

Study Evaluating Inotuzumab Ozogamicin In Acute Lymphocytic Leukemia

A Study Evaluating the Safety, Tolerability, and Pharmacokinetics of GDC-0425 Administered With and Without Gemcitabine in Patients With Refractory Solid Tumors or Lymphoma

Find Trials by Condition in Detroit

Chemotherapy With or Without Additional Chemotherapy and/or Radiation Therapy in Treating Children With Newly Diagnosed Hodgkin's Disease

Safety and Efficacy of AVP-923 in PBA Patients With ALS or MS

Effect of NovoTTF-100A Together With Temozolomide in Newly Diagnosed Glioblastoma Multiforme (GBM)

Efficacy and Safety of 20 mg Sumatriptan Powder Delivered Intranasally With the Bi-directional Device Compared With 100 mg Sumatriptan Tablets in Adults With Acute Migraine With or Without Aura

Progel Vascular Sealant

A 12-Week Study in Asthmatic Children Ages 6 to <12 Years, Investigating the Efficacy and Safety of Symbicort pMDI 80/2.25 μg and Symbicort pMDI 80/4.5 μg, Compared With Budesonide pMDI 80 μg

Pharmacokinetics and Pharmacodynamics of Dexmedetomidine in Pediatrics Subjects

Capecitabine and Vorinostat in Treating Patients With Recurrent and/or Metastatic Head and Neck Cancer

Healing With Venlafaxine After Injury (HELP)

A Study to Assess the Effect and Safety of AZD6765 in Patients With Major Depressive Disorder

Phase II Study of VS-6063 in Patients With KRAS Mutant Non-Small Cell Lung Cancer

3-year Follow-up Study in Patients Previously Treated With TMC435-Containing Regimen for the Treatment of Hepatitis C Virus Infection

Safety and Efficacy of Cariprazine for Bipolar I Disorder

Study of LY2784544 Testing Alternative Dosing in Participants With Myeloproliferative Neoplasms

Depression in Alzheimer's Disease-2

Safety, Tolerability and Efficacy of Etelcalcetide in Hemodialysis Patients With Secondary Hyperparathyroidism

Prolonging Remission in Depressed Elderly (PRIDE)

BD FlowSmart™ Subcutaneous Insulin Infusion Set User Preference and Claims Study