Clinical Trials in Detroit

Showing 8021-8040 of 19,719 trials

A Phase 1/2, Open-label, Multicenter, Dose Escalation and Expansion Study of SLC-3010 Monotherapy and in Combination

NCT05525247

This is a Phase 1/2, open-label, multicenter, dose escalation and expansion study, evaluating the safety, tolerability, pharmacokinetic, preliminary anti-tumor activity, and effects on pharmacodynamic markers following administration of SLC-3010 as monotherapy and in combination with gemcitabine, in patients with various advanced solid tumors.

Advanced Solid Tumor

Selecxine420 participantsStarted Dec 2022

Sarasota, Florida, United States • Detroit, Michigan, United States • Oklahoma City, Oklahoma, United States +6 more locations

WITHDRAWNPhase 2< 1 mile

INCAGN01876 in Combination With Immunotherapy in Participants With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

NCT05359692

The purpose of this study is to determine the safety, tolerability, efficacy, PK and pharmacodynamics of INCAGN01876 when given in combination with retifanlimab. The study will consist of 2 parts: a safety lead-in part (Part 1) followed by a dose expansion part (Part 2).

Metastatic Head and Neck Squamous Cell CarcinomaAdvanced MalignanciesRecurrent Head and Neck Squamous Cell Carcinoma

Incyte Biosciences International SàrlStarted Mar 2023

Birmingham, Alabama, United States • La Jolla, California, United States • Palo Alto, California, United States +14 more locations

A Phase 1/2, Open-label, Multicenter, Dose Escalation and Expansion Study of SLC-3010 Monotherapy and in Combination

INCAGN01876 in Combination With Immunotherapy in Participants With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

Find Trials by Condition in Detroit

Study of Ipatasertib or Apitolisib With Abiraterone Acetate Versus Abiraterone Acetate in Participants With Castration-Resistant Prostate Cancer Previously Treated With Docetaxel Chemotherapy

Early Feasibility Study for the Foldax Tria Aortic Heart Valve

Evaluating the Role of the Guidewire in Peripheral Intravenous Access

Oral CF101 and Methotrexate Treatment in Rheumatoid Arthritis Patients

A Study of Combination Therapies With Viagenpumatucel-L (HS-110) in Patients With Non-Small Cell Lung Cancer

A Phase II Study Evaluating the Safety and Efficacy of Subcutaneous Plerixafor

Addressing Dementia Via Agitation-Centered Evaluation

Study of Sotatercept for the Treatment of Chemotherapy Induced Anemia in Patients With Metastatic Breast Cancer (MK-7962-012)

Study of the Safety and Efficacy of PRX-102 Compared to Agalsidase Beta on Renal Function

Trametinib, Fluorouracil, and Radiation Therapy Before Surgery in Treating Patients With Stage II-III Rectal Cancer

A Study of a Personalized Cancer Vaccine Targeting Shared Neoantigens

Study of Safety and Efficacy of Multiple Doses of CFZ533 in Two Distinct Populations of Patients With Sjogren's Syndrome

Multi-Center Pilot Study of Cutera truSculpt Device

Multi-Center Pilot Study of truSculpt Device

Human Epilepsy Project 2: Resistant Focal Seizures Study

A Dose-escalation Study to Evaluate the Safety and Clinical Activity of PBCAR269A, With or Without Nirogacestat, in Study Participants With Relapsed/Refractory Multiple Myeloma

An add-on Study to the FIGARO-DKD Study Called FIGARO-BM to Learn About the Link Between Biomarkers (Substances in the Blood Used as Indicators of Biological Processes, Disease Processes or Responses to Medication) and Finerenone in FIGARO-DKD Participants

Pilot Study of Multi-wavelength Laser for Tattoo Removal