Clinical Trials in Detroit

Showing 3921-3940 of 19,719 trials

Efficacy and Safety of the CG-100 Intraluminal Bypass Device

NCT04184973

A randomized trial to assess the safety and efficacy of CG-100 for reducing stoma creation rate in subjects undergoing mesorectal excision.

Rectal CancerRectal TumorRectal/Anal

Colospan Ltd.250 participantsStarted Jun 2020

Orange, California, United States • San Diego, California, United States • Aurora, Colorado, United States +11 more locations

RECRUITINGPhase 3< 1 mile

To Evaluate Efficacy of Belinostat or Pralatrexate in Combination Against CHOP Alone in PTCL

NCT06072131

Part 1: This is a 5 Arm study primarily to determine the best dose out of the two dose levels of Belinostat and Pralatrexate combined with CHOP/COP in newly diagnosed PTCL patients based on Safety for part 2 study. Part 2 (Efficacy and Safety): This is a 3 Arm study. Patients with previously untreated PTCL will be randomized 1:1:1 into 1 of 3 treatment groups: 2 experimental treatment groups (Bel-CHOP or Fol-COP) or 1 active comparator treatment group (CHOP). Patients will be treated for up to 6 cycles. The primary objective is to compare the Progression Free Survival of patients with newly diagnosed PTCL treated for up to 6 cycles with Beleodaq (belinostat) in combination with CHOP (Bel-CHOP) or Folotyn (pralatrexate injection) in combination with COP (Fol-COP) to CHOP alone.

Peripheral T Cell Lymphoma

Acrotech Biopharma Inc.504 participantsStarted Oct 2023

Clovis, California, United States • Santa Monica, California, United States • Aurora, Colorado, United States +66 more locations

Efficacy and Safety of the CG-100 Intraluminal Bypass Device

To Evaluate Efficacy of Belinostat or Pralatrexate in Combination Against CHOP Alone in PTCL

Find Trials by Condition in Detroit

CaRi-Heart Assessment of Risk and Evaluation of Inflammation in Coronary CT Angiography (CARE-CCTA)

A Phase 3 Study of Zalunfiban in Subjects With ST-elevation MI

An Efficacy, Safety, and Tolerability Study of Veligrotug (VRDN-001), in Participants With Chronic Thyroid Eye Disease (TED) (THRIVE-2)

An Extension Study to Evaluate the Long-term Safety and Efficacy of Pegcetacoplan (APL-2) in Subjects With Geographic Atrophy Secondary to AMD

Lithium Disilicate Crowns Study

Network Connectivity and Temporal Processing in Adolescents Who Stutter

Tissue Reinforcement for Breast Reconstruction (TRBR) Pivotal Clinical Study (REDEFINE)

EValuating trEatment RESponses of Dupilumab Versus Omalizumab in Type 2 Patients

Open Label Extension of Efgartigimod in Adults With Post-COVID-19 POTS

The Myelin Disorders Biorepository Project

First-In-Human Study to Evaluate Safety, Tolerability, and PK of Intravenous ATB200 Alone and When Co-Administered With Oral AT2221

A FIH Study of PF-07284890 in Participants With BRAF V600 Mutant Solid Tumors With and Without Brain Involvement

Aspirin in Preventing Disease Recurrence in Patients With Barrett Esophagus After Successful Elimination by Radiofrequency Ablation

Safety and Efficacy Study of Intracystic TARA-002 for the Treatment of Lymphatic Malformations in Participants 6 Months to Less Than 18 Years of Age

Study of Subcutaneous (SC) Belimumab in Pediatric Participants With Systemic Lupus Erythematosus (SLE)

Non-Operative Management and Early Response Assessment in Rectal Cancer

A Study of LY3127804 With Ramucirumab in Participants With Advanced Solid Tumors

Multidisciplinary Translational Approach to Investigate Mechanisms Predictors & Prevention of Persistent PTH