Clinical Trials in Detroit

Showing 3381-3400 of 19,719 trials

Safely Optimizing Body Weight With TCMCB07 in Patients With Newly Diagnosed Metastatic Colorectal Cancer Undergoing Chemotherapy

NCT06937177

This is a randomized, double-blind, placebo-controlled study of B07, administered daily by subcutaneous (SC) injection, in up to 120 patients with newly diagnosed metastatic colorectal cancer. This study will evaluate different doses of B07 on weight, body composition and BMI in patients with sub-optimal BMIs (≤ 29 kg/m\^2). Treatment will start at the second cycle of first-line cancer chemotherapy and continue for 12-weeks with the goal of maintaining body weight and muscle mass in patients undergoing chemotherapy relative to control.

Cancer Weight Loss

Endevica Bio120 participantsStarted Apr 2025

Tucson, Arizona, United States • Los Angeles, California, United States • Los Angeles, California, United States +14 more locations

Not Yet Recruiting< 1 mile

Study of Oral Food Challenge Biomarkers (SAFER)

NCT07279467

This is a multi-center, mechanistic study. It is designed to learn more about signs in the body, called biomarkers, that might show if someone will have a reaction to peanut during a feeding test. The trial will enroll children ages 12 months to17 years old who are suspected of having an allergy to peanut. The primary objective is to identify a biomarker (or a combination of biomarkers) that will predict oral food challenge (OFC) (feeding test) results for participants with suspected peanut allergy.

Allergy

National Institute of Allergy and Infectious Diseases (NIAID)500 participantsStarted Apr 2026

Little Rock, Arkansas, United States • Palo Alto, California, United States • Chicago, Illinois, United States +7 more locations

Safely Optimizing Body Weight With TCMCB07 in Patients With Newly Diagnosed Metastatic Colorectal Cancer Undergoing Chemotherapy

Study of Oral Food Challenge Biomarkers (SAFER)

Find Trials by Condition in Detroit

Ganciclovir to Prevent Reactivation of Cytomegalovirus in Patients With Acute Respiratory Failure and Sepsis

A Study to Assess the Long-Term Safety and Efficacy of Donidalorsen in the Prophylactic Treatment of Hereditary Angioedema (HAE)

Extension Study to Evaluate Safety and Tolerability of Oral Dersimelagon (MT-7117) in Subjects With Erythropoietic Protoporphyria (EPP) or X-Linked Protoporphyria (XLP)

A Study Evaluating The Efficacy and Safety of Neoadjuvant Immunotherapy Combinations in Patients With Surgically Resectable Hepatocellular Carcinoma

A Research Study to Compare Two Semaglutide Medicines in People With Type 2 Diabetes

A Study of HBS-201 (Pitolisant Delayed-release)

Mobile Platform for Optimizing Wellness and Engagement in Recovery

Adversity, Brain and Opioid Use Study

A Study of Olezarsen (Formerly Known as AKCEA-APOCIII-LRX) Administered to Adults With Familial Chylomicronemia Syndrome (FCS) Previously Treated With Volanesorsen

Abatacept as GVHD Prophylaxis Phase 2

Open Label, Dose-finding, Pharmacokinetics, Safety and Tolerability Study of Oritavancin in Pediatric Participants With Suspected or Confirmed Bacterial Infections

A Study of Zigakibart in Adults With IgA Nephropathy

A Study to Assess the Safety, Tolerability, and Efficacy of Rocatinlimab in Adolescent Participants With Moderate-to-severe Atopic Dermatitis (AD)

A Research Study to Look at How Well CagriSema Helps People Living With Obesity Lose Weight and Maintain Weight Loss in the Long-term

A Trial to Evaluate the Efficacy and Safety of PQ912 in Patients With Early AD

VIRTUUS Children's Study

A Study of Nofazinlimab (CS1003) in Subjects With Advanced Hepatocellular Carcinoma

UNITY VCS Vitreoretinal Surgery