Clinical Trials in Denver

Showing 15361-15380 of 18,161 trials

Gamma Secretase Inhibitor RO4929097 in Previously Treated Metastatic Pancreas Cancer

NCT01232829

This phase II trial is studying how well RO4929097 (gamma-secretase/Notch signalling pathway inhibitor RO4929097) works in treating patients with previously treated metastatic pancreatic cancer. RO4929097 may stop the growth of tumor cells by blocking some enzymes needed for cell growth.

Adenocarcinoma of the PancreasRecurrent Pancreatic CancerStage IV Pancreatic Cancer

National Cancer Institute (NCI)18 participantsStarted Oct 2010

Aurora, Colorado, United States • Denver, Colorado, United States • Baltimore, Maryland, United States

COMPLETED< 1 mile

A Health & Wellness Intervention for Individuals With Traumatic Brain Injury (TBI)

NCT01334398

The primary goal of the proposed study is to evaluate the efficacy of a replicable community-based group intervention, designed to address both general wellness and specific TBI health-related issues. Emphasis is placed on goal setting to develop healthy habits, utilizing problem solving strategies, learning means of maintaining progress and setting new goals. Facilitators will utilize approaches aimed at maximizing participant self-efficacy, reducing barriers to health promotion, and developing personal resources. A randomized wait-list control group design will be used to evaluate the efficacy of the intervention. It is hypothesized that individuals with TBI who participate in the intervention group will report increased health promoting behaviors, health related self-efficacy, health-related quality of life, level of participation, and greater perceived wellness and satisfaction with life as compared to the control group.

Traumatic Brain Injury

VA Eastern Colorado Health Care System74 participantsStarted Oct 2008

Denver, Colorado, United States

Gamma Secretase Inhibitor RO4929097 in Previously Treated Metastatic Pancreas Cancer

A Health & Wellness Intervention for Individuals With Traumatic Brain Injury (TBI)

Find Trials by Condition in Denver

Identifying the Needs of Operation Enduring Freedom/Operation Iraqi Freedom (OEF/OIF) Veterans and Their Families: TBI and Co-Occurring Behavioral Health Issues

Urinary Heparanase Activity as a Predictor of Acute Kidney Injury in Critically Ill Adults

Everolimus and Octreotide in Patients With Advanced Carcinoid Tumor

CARTO® 3 System and Real Time Intracardiac Ultrasound

Intramuscular Depot Formulation of Aripiprazole as Maintenance Treatment in Patients With Schizophrenia

Co-administration of Olodaterol Respimat® and Tiotropium Handihaler®

Ponatinib in Newly Diagnosed Chronic Myeloid Leukemia (CML) (EPIC)

Study of a Single Dose of Menactra® Vaccine 4-6 Years After Prior Menactra Vaccine

A Multi-Center Study To Evaluate Multiple Doses of NT100 Following IVF In Women With Repeated IVF Failures (Thrive-IVF)

A Study to Assess the Potential Effects of Rifampin on the Pharmacokinetics of Trabectedin in Patients With Advanced Malignancies

Naturlose (D-Tagatose) Efficacy Evaluation Trial

Avelox for Treatment of Elderly Patients With Community Acquired Pneumonia

A Study of the Safety and Efficacy of Two Doses of Naltrexone SR/Bupropion SR and Placebo in Overweight and Obese Subjects

Monotherapy Pazopanib in Subjects With Advanced Non-Small Cell Lung Cancer

Open-label Extension Evaluating Methylphenidate Hydrochloride Extended Release in Adults With Attention Deficit/Hyperactivity Disorder

DPBRN Reasons for Placing the First Restoration on Permanent Tooth Surfaces

A Safety Study of Oral Netupitant and Palonosetron for the Prevention of Nausea and Vomiting

Linagliptin in Combination With Metformin in Treatment Naive Patients With Type 2 Diabetes Mellitus and Insufficient Glycaemic Control