Clinical Trials in Denver

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PRO 140 for Human Immunodeficiency Virus Infection

NCT02257788

PRO 140 2103 is a multicenter, randomized parallel group study, conducted in male and female adult subjects infected with CCR5-tropic HIV-1.

HIV

Drexel UniversityStarted Sep 2014

Stanford, California, United States • Denver, Colorado, United States • St Louis, Missouri, United States +4 more locations

COMPLETEDPhase 3< 1 mile

The Effect of Liraglutide Compared to Sitagliptin, Both in Combination With Metformin on Glycaemic Control in Subjects With Type 2 Diabetes Mellitus

NCT00700817

This trial is conducted in Europe and North America. The aim of this trial is to compare the effect on blood sugar control of liraglutide or sitagliptin, both in combination with metformin, in subjects with type 2 diabetes inadequately controlled with metformin alone. The trial has been extended by 52 weeks. The extension will consist of two 26-week periods: 1. Week 27-52 after randomisation \- All subjects will continue receiving sitagliptin or liraglutide at unchanged dose and dosing regimen. 2. Week 53-78 after randomisation * Subjects receiving sitagliptin at the end of week 52 after randomisation will discontinue sitagliptin and will be randomised 1:1 to liraglutide 1.2 mg/day or liraglutide 1.8 mg/day. Liraglutide will be initiated at a dose of 0.6 mg/day, and increased to 1.2 mg/day or 1.8 mg/day in weekly intervals. * Subjects receiving liraglutide 1.2 mg/day or 1.8 mg/day at the end of week 52 after randomisation will continue the treatment at unchanged dose and dosing regimen. Trial completion is planned for June 2010.

DiabetesDiabetes Mellitus, Type 2

Novo Nordisk A/S665 participantsStarted Jun 2008

Birmingham, Alabama, United States • Escondido, California, United States • Fresno, California, United States +163 more locations

PRO 140 for Human Immunodeficiency Virus Infection

The Effect of Liraglutide Compared to Sitagliptin, Both in Combination With Metformin on Glycaemic Control in Subjects With Type 2 Diabetes Mellitus

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The Effect of Somatropin Treatment in Adult Patients on Chronic Dialysis

Comparison of NN1250 With Insulin Glargine in Subjects With Type 2 Diabetes

Study of Oxaliplatin/5-FU/Leucovorin Plus Vatalanib Versus Oxaliplatin/5-FU/Leucovorin in Patients With Previously Treated Metastatic Colorectal Cancer

A Study of the Experimental Drug BKM120 With Paclitaxel in Patients With HER2 Negative, Locally Advanced or Metastatic Breast Cancer, With or Without PI3K Activation

Radiation Therapy or Observation After Chemotherapy in Treating Patients With Stage IV Non-Small Cell Lung Cancer

The Effect of Insulin Detemir in Combination With Liraglutide and Metformin Compared to Liraglutide and Metformin in Subjects With Type 2 Diabetes

The Effect of Liraglutide Versus Placebo When Added to Basal Insulin Analogues With or Without Metformin in Subjects With Type 2 Diabetes

Efficacy of Web-based Pain Self-management for Adolescents With Juvenile Idiopathic Arthritis

A Trial Comparing the Efficacy, Patient-reported Outcomes and Safety of Insulin Degludec 200 U/mL vs Insulin Glargine in Subjects With Type 2 Diabetes Mellitus Requiring High-dose Insulin

16 Week Efficacy and 2 Year Long Term Safety and Efficacy of Secukinumab in Patients With Active Ankylosing Spondylitis

SuperNOVA Clinical Stenting Trial

Haemophilia Patients With Inhibitors Being Treated for Acute Joint Bleeds

PRESERVE-Zenith® Iliac Branch System Clinical Extended Study

Engaging Care for HIV-infected Adolescent Females.

Integrated Treatment of Marijuana Abuse for HIV+ Youth

Lapatinib and Radiation for Stage III-IV Head and Neck Cancer Patients Who Cannot Tolerate Concurrent Chemotherapy

Evaluation of GSK561679 in Women With Post-Traumatic Stress Disorder

Multi-national Study Investigating the Effect and Safety of rFXIII on Transfusion Needs in Patients Undergoing Heart Surgery