Clinical Trials in Denver

Showing 13561-13580 of 18,161 trials

Phase 1b/2 Study of Oprozomib in Combination With Sorafenib in Subjects With Advanced Hepatocellular Carcinoma

NCT02227914

The purpose of Phase 1b of the study is to determine the maximum tolerated dose, pharmacokinetics (PK) and pharmacodynamics (PDn) and assess the safety, tolerability and activity of oprozomib in combination with sorafenib in subjects with advanced hepatocellular carcinoma (HCC). The purpose of Phase 2 of the study is to evaluate the efficacy of oprozomib in combination with sorafenib versus sorafenib alone and to compare the key outcome measures for subjects with advanced HCC.

Advanced Hepatocellular Carcinoma

AmgenStarted Dec 2014

Burlington, California, United States • Denver, Colorado, United States • Miami, Florida, United States +3 more locations

COMPLETEDPhase 2< 1 mile

Phase 2 Study of Carfilzomib in Relapsed Multiple Myeloma

NCT00530816

To evaluate the best overall response rate, safety and tolerability of carfilzomib in patients with relapsed or refractory multiple myeloma.

Multiple Myeloma

Amgen164 participantsStarted Sep 2007

Scottsdale, Arizona, United States • Beverly Hills, California, United States • Laguna Hills, California, United States +27 more locations

Phase 1b/2 Study of Oprozomib in Combination With Sorafenib in Subjects With Advanced Hepatocellular Carcinoma

Phase 2 Study of Carfilzomib in Relapsed Multiple Myeloma

Find Trials by Condition in Denver

Duloxetine in Treating Peripheral Neuropathy Caused by Chemotherapy in Patients With Cancer

Targeting Acute Congestion With Tolvaptan in Congestive Heart Failure

Inhibitor Development in Patients With Hemophilia A Undergoing Surgery

Technical Efficacy of a Direction Specific Radiofrequency Device in the Performance of Lumbar Medial Branch Neurotomies

A Study To Investigate Safety And Efficacy Of CP-690,550 For Induction Therapy In Subjects With Moderate To Severe Crohn's Disease

Characterization of Dermal Reactions in Pediatric Patients With ADHD Using DAYTRANA

Impact of Dietary Intervention on Weight Change in Subjects With Type 2 Diabetes

Efficacy and Safety Study of Benralizumab Added to High-dose Inhaled Corticosteroid Plus LABA in Patients With Uncontrolled Asthma

Safety and Efficacy Study of DSP-Visulex for the Treatment of Anterior Uveitis

PREventative Study Against URate-lowering Drug-induced Gout Exacerbations 1

Study of the Safety and Effectiveness of Rilonacept for the Prevention of Gout Flares

Evaluate the Efficacy &Safety of Methylphenidate Transdermal System (MTS) in Adolescents Aged 13-17 Years With ADHD

Atorvastatin (Lipitor) Therapy in Patients With Clinically Isolated Syndrome (CIS) at Risk for Multiple Sclerosis

Pulsed Radiofrequency Energy to Treat Post-Bunionectomy Pain

Effect of Squalamine Lactate Ophthalmic Solution, 0.2% in Subjects With Neovascular Age-Related Macular Degeneration

Safety and Pharmacology Study of SNX-5422 in Subjects With Refractory Hematological Malignancies

Genome-Wide Gene Expression Profiling of Patients With ITP Receiving Thrombopoietin Mimetics

Study to Evaluate the Efficacy, Safety and Pharmacokinetics of PT001, PT003, and PT005 Following Chronic Dosing (7 Days) in Patients With Moderate to Very Severe Chronic Obstructive Pulmonary Disease (COPD)