Clinical Trials in Denver

Showing 5521-5540 of 18,161 trials

P-PSMA-101 CAR-T Cells in the Treatment of Subjects With Metastatic Castration-Resistant Prostate Cancer (mCRPC) and Advanced Salivary Gland Cancers (SGC)

NCT04249947

An open-label, multi-center, single and cyclic ascending dose study of P-PSMA-101 autologous CAR-T cells in patients with mCRPC and SGC.

Prostatic Neoplasms, Castration-ResistantNeoplasms by Histologic TypeNeoplasms, Prostate+14 more

Poseida Therapeutics, Inc.40 participantsStarted Feb 2020

Duarte, California, United States • San Diego, California, United States • San Francisco, California, United States +7 more locations

Active Not Recruiting8.4 miles

Neuroblastoma Precision Trial

NCT02868268

This proposal sets forth the platform for a Precision Medicine clinical trial through the New Approaches to Neuroblastoma Therapy (NANT) consortium. The plan is to utilize NANT's established multi-institutional infrastructure and Translational Genomics Research Institute GEM sequencing platform for acquisition and gene panel sequencing of relapsed biological specimens in relapsed/refractory neuroblastoma (rNB) including those obtained from the bone, bone marrow or soft tissue. Our primary aim is to identify subgroups of rNB patients who have potentially targetable genetic (ALK, MAPK pathway, Metabolic-related genes) and/or immunologic (tumor-associated macrophage infiltration and/or programmed death ligand \[PD-L1\] expression) biomarkers in rNB. Additional potential novel biomarkers will also be evaluated and reported in this cohort of patients.

Neuroblastoma

New Approaches to Neuroblastoma Therapy Consortium93 participantsStarted Aug 2016

Los Angeles, California, United States • San Francisco, California, United States • Aurora, Colorado, United States +8 more locations

P-PSMA-101 CAR-T Cells in the Treatment of Subjects With Metastatic Castration-Resistant Prostate Cancer (mCRPC) and Advanced Salivary Gland Cancers (SGC)

Neuroblastoma Precision Trial

Find Trials by Condition in Denver

Safety and Effectiveness of the MiniMed™ 780G System With DS5 CGM

IO-202 as Monotherapy and IO-202 Plus Azacitidine ± Venetoclax in Patients in AML and CMML

Pulsed Field Ablation to Irreversibly Electroporate Tissue and Treat AF

INFINITY™Total Ankle Replacement Follow-up

Evaluation of the Phased Radio Frequency Ablation System

A Study Evaluating Safety and Tolerability, and Pharmacokinetics of Navitoclax Monotherapy and in Combination With Ruxolitinib in Participants With Myeloproliferative Neoplasm

Evaluation of Brimonidine Tartrate/Ketotifen Fumarate Combination for the Treatment of Allergic Conjunctivitis

Myeloma-Developing Regimens Using Genomics (MyDRUG)

Intracardiac CrYoablation for AtrioVentricular Nodal Reentrant Tachycardia

COVID-19 Vaccine Response in Sickle Cell Disease

Evaluation of Lasofoxifene Combined With Abemaciclib in Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation

A Study of KB-0742 in Participants With Relapsed or Refractory Solid Tumors Including Platinum Resistant High Grade Serous Ovarian Cancer (HGSOC)

Trametinib in Treating Patients With Advanced Cancer With or Without Hepatic Dysfunction

TAC T-cells for the Treatment of Claudin 18.2 Positive Solid Tumors (TACTIC-3)

Mapping the Genotype, Phenotype, and Natural History of Phelan-McDermid Syndrome

Evaluation of the Safety and Effectiveness of Bilateral Exablate Ablation of the Pallidothalamic Tract (PTT) for the Treatment of the Motor Complications of Parkinson's Disease (PD)

A Study to Assess the Pharmacodynamics of VK0214 in Male Subjects With AMN

Study of the Efficacy of Lurasidone in Cognitive Functioning in Bipolar Patients