Clinical Trials in Denver

Showing 5121-5140 of 18,161 trials

Open-Label Extension: Tolerability and Effects of ALK-001 on Stargardt Disease (TEASE)

NCT04239625

The purpose of this open-label, multicenter study is to determine the long-term safety, pharmacokinetics and effects of ALK-001 (C20-D3-retinyl acetate) on the progression of Stargardt disease. This study is an extension of NCT02402660 and enrolls participants who are at least 8 years old. Enrollment is by invitation only. Funding Source - FDA OOPD

Stargardt DiseaseStargardt Macular DegenerationStargardt Macular Dystrophy+1 more

Alkeus Pharmaceuticals, Inc.200 participantsStarted Dec 2019

Phoenix, Arizona, United States • Los Angeles, California, United States • Aurora, Colorado, United States +5 more locations

COMPLETED8.4 miles

Linking Endotypes and Outcomes in Pediatric Acute Respiratory Distress Syndrome

NCT04113434

The overall goal of the study is to risk stratify pediatric Acute Respiratory Distress Syndrome (ARDS) patients and to identify sub-phenotypes with shared biology in order to appropriately target therapies in future trials. This is a prospective, multicenter study of 500 intubated children with ARDS, with planned blood collection within 24 hours of ARDS onset and subsequent measurement of plasma protein biomarkers and peripheral blood gene expression.

Acute Respiratory Distress Syndrome

Children's Hospital of Philadelphia500 participantsStarted Jan 2020

Little Rock, Arkansas, United States • Aurora, Colorado, United States • Miami, Florida, United States +13 more locations

Open-Label Extension: Tolerability and Effects of ALK-001 on Stargardt Disease (TEASE)

Linking Endotypes and Outcomes in Pediatric Acute Respiratory Distress Syndrome

Find Trials by Condition in Denver

A Study to Investigate the Efficacy and Safety of Canagliflozin in Children and Adolescents (>=10 to <18 Years) With Type 2 Diabetes Mellitus

Efficacy Study of Nivolumab Compared to Ipilimumab in Prevention of Recurrence of Melanoma After Complete Resection of Stage IIIb/c or Stage IV Melanoma

Dapagliflozin Treatment in Type 2 Diabetes

HOme PElvic Floor Improvement Trainer Trial

Can You Breathe Your Way To Better Health?

A Trial of Setanaxib in Patients With Primary Biliary Cholangitis (PBC) and Liver Stiffness

The Celljuvant Study: A Phase 3 Immunogenicity and Safety Study of aQIVc Vaccine in Adults Aged 50 Years and Older

Burn Validation Study

A Multiple-dose Study of ASP8374, an Immune Checkpoint Inhibitor, as a Single Agent and in Combination With Pembrolizumab in Subjects With Advanced Solid Tumors

A Study of Esketamine Nasal Spray, Administered as Monotherapy, in Adult Participants With Treatment-resistant Depression

Predictive Analytics and Clinical Decision Support to Improve PrEP Prescribing

User Acceptability Evaluation of Pseudophakic Patients Previously Implanted With the TECNIS Odyssey IOL

A Study of Seltorexant as Adjunctive Therapy to Antidepressants in Adolescents With Major Depressive Disorder Who Have an Inadequate Response to Selective Serotonin Reuptake Inhibitor (SSRI) and Psychotherapy

Visualization of the STN and GPi for DBS

Phase 2b Study of MBS2320 in Participants With Methotrexate-Refractory RA

Assessment of a Non-invasive Device in the Management of Open Abdomen (AbCLO)

A Study of JNJ-73763989 + Nucleos(t)Ide Analog in Participants Co-Infected With Hepatitis B and Hepatitis D Virus

A Standard of Care Study of Patients With Major Depressive Disorder Who Have Had an Inadequate Response to a Selective Serotonin Reuptake/Serotonin-Norepinephrine Reuptake Inhibitor Antidepressant